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Mouth cancer data faked, journal says.


A study claiming to find that anti-inflammatory drugs including ibuprofen reduce the risk of mouth cancer in smokers was based on falsified data, according to the medical journal that punished the research.

Jon Sudbo of the Norwegian Radium radium (rā`dēəm) [Lat. radius=ray], radioactive metallic chemical element; symbol Ra; at. no. 88; at. wt. 226.0254; m.p. 700°C;; b.p. 1,140°C;; sp. gr. about 6.0; valence +2. Radium is a lustrous white radioactive metal.  Hospital and the University of Oslo The University of Oslo (Norwegian: Universitetet i Oslo, Latin: Universitas Osloensis) was founded in 1811 as Universitas Regia Fredericiana (the Royal Frederick University  presented the findings last year at a cancer-research meeting in Anaheim, Calif. (SN: 5/7/05, p. 302) and in the Oct. 15, 2005 Lancet. Through his lawyer, Sudbo has admitted that he made up the 908 patients cited in the paper. Lancet is seeking a retraction.

Other papers authored by Sudbo are also under scrutiny, and officials of the Norwegian Radium Hospital said that they are reviewing all of Sudbo's research.

A study in the April 26, 2001 New England Journal of Medicine The New England Journal of Medicine (New Engl J Med or NEJM) is an English-language peer-reviewed medical journal published by the Massachusetts Medical Society. It is one of the most popular and widely-read peer-reviewed general medical journals in the world.  (NEJM NEJM New England Journal of Medicine ) showed photographs of two supposedly distinct types of abnormal mouth tissue. In a statement published online Jan. 20, NEJM says that these photos were the same and that the journal is awaiting the results of the review by Sudbo's institution. The state is also in doubt.

Moreover, in the March 20, 2005 Journal of Clinical Oncology The Journal of Clinical Oncology is a medical journal published by the American Society of Clinical Oncology. The Journal was founded in 1983 and publishes original research and review articles on topics relating to cancer. It is published 3 times a month. , Sudbo falsely claimed to have obtained blood samples from volunteers, according to Sudbo's lawyer.

The revelation comes on the heels of another ease of fraud in medical science. Recently, South Korean researcher WooSuk Hwang--who claimed to have cloned the first human embryonic stem cell Embryonic stem cells (ES cells) are stem cells derived from the inner cell mass of an early stage embryo known as a blastocyst. Human embryos reach the blastocyst stage 4-5 days post fertilization, at which time they consist of 50-150 cells.

ES cells are pluripotent.
 lines--was found to have faked the data in two studies published in Science (SN: 12/24 & 31/05, p. 406; 1/14/06, p. 20). Science has retracted both papers.--N.S.
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Title Annotation:BIOMEDICINE
Publication:Science News
Article Type:Brief Article
Geographic Code:1USA
Date:Feb 11, 2006
Words:261
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