More promise. (Letters).Another new anti-HIV drug in the non-nucleoside reverse transcriptase inhibitor Noun 1. non-nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs NNRTI (NNRTI NNRTI Non-nucleoside reverse transcriptase inhibitor, see there ) class that has shown promise ("Full Pipeline: Success of experimental AIDS drugs offers promise of future therapies," SN: 2/22/03, p. 117) is TMC125. You don't mention this drug, but it has been shown in trial studies to have replaced five drugs for drug-resistant patients, it produces a large drop in viral load, and it has been shown to have very mild side affects. I found this particularly interesting because the current protease inhibitors and some NNRTI drugs are known to cause abnormal redistribution of body fat and potentially fatal liver toxicities. G. DAVID David, in the Bible David, d. c.970 B.C., king of ancient Israel (c.1010–970 B.C.), successor of Saul. The Book of First Samuel introduces him as the youngest of eight sons who is anointed king by Samuel to replace Saul, who had been deemed a failure. BACA Baca (bā`kə), in the Bible, allegorical name of a valley. The English expression "vale (or valley) of tears" may be a translation of this, through the Vulgate. , COLORADO SPRINGS, COLO. |
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