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Molecular neurosurgery with targeted toxins.


Molecular neurosurgery neurosurgery /neu·ro·sur·gery/ (noor´o-sur?jer-e) surgery of the nervous system.

Surgery on any part of the nervous system.
 with targeted toxins.

Ed. by Ronald G. Wiley and Douglas A. Lappi.

Humana Press Inc.


311 pages




Targeted cytotoxins are used in experimental neurobiology Neurobiology

Study of the development and function of the nervous system, with emphasis on how nerve cells generate and control behavior. The major goal of neurobiology is to explain at the molecular level how nerve cells differentiate and develop their
 to produce neural lesions of unprecedented selectivity to match the complexity of the organization of the nervous system itself. Researchers in the neurosciences, psychology, pharmaceuticals, and other specialties introduce the considerations and background of the toxins, then describe examples of using the immunotoxin immunotoxin /im·mu·no·tox·in/ (im´u-no-tok?sin) any antitoxin.

A hybrid molecule formed by binding a toxin to a monoclonal antibody, used to destroy tumor cells.
 192 IgG-saporin to make lesions on the cholinergic cholinergic /cho·lin·er·gic/ (ko?lin-er´jik)
1. parasympathomimetic; stimulated, activated, or transmitted by choline (acetylcholine); said of the sympathetic and parasympathetic nerve fibers that liberate acetylcholine at a
 basal forebrain, the anti-DBH-saporin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin to produce narcoleptic animals, a variety of saporin conjugates in pain research, and cholera toxin B chain- saporin to produce a model of CNS See Continuous net settlement.


See continuous net settlement (CNS).

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Publication:SciTech Book News
Article Type:Book Review
Date:Sep 1, 2005
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