Modern Organic Synthesis In The Laboratory Will Be Useful For Both Graduate Students And Professors In Organic Chemistry.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c81714) has announced the addition of "Modern Organic Synthesis in the Laboratory" to their offering. Searching for reaction in organic synthesis has been made much easier in the current age of computer databases. However, the dilemma now is which procedure one selects among the ocean of choices. Especially for novices in the laboratory, it becomes a daunting daunt tr.v. daunt·ed, daunt·ing, daunts To abate the courage of; discourage. See Synonyms at dismay. [Middle English daunten, from Old French danter, from Latin task to decide what reaction conditions to experiment with first in order to have the best chance of success. This collection intends to serve as an "older and wiser lab-mate" one could have by compiling many of the most commonly used experimental procedures in organic synthesis. With chapters that cover such topics as functional group manipulations, oxidation, reduction, and carbon-carbon bond formation, Modern Organic Synthesis in the Laboratory will be useful for both graduate students and professors in organic chemistry and medicinal chemists in the pharmaceutical and agrochemical industries. About the Authors Jie Jack Li, Medicinal Chemist, Pfizer Global Research and Development , Chris Limberakis, Medicinal Chemist, Pfizer Global Research and Development , and Derek A. Pflum, Chemical Research and Development Group, Pfizer Global Research and Development Contents: Foreword Abbreviations and Acronyms 1 Fundamental Techniques 1.1 Safety! 1.2 Useful Preparations 1.3 Chromatography 1.4 Crystallization 1.5 Residual Solvent Peaks in Nuclear Magnetic Resonance nuclear magnetic resonance: see magnetic resonance. nuclear magnetic resonance (NMR) Selective absorption of very high-frequency radio waves by certain atomic nuclei subjected to a strong stationary magnetic field. 2 Functional Group Manipulations 2.1 Alcohol Oxidation State 2.2 Ketone ketone (kē`tōn), any of a class of organic compounds that contain the carbonyl group, C=O, and in which the carbonyl group is bonded only to carbon atoms. Oxidation State 2.3 Acid Oxidation State 3 Oxidation 3.1 Alcohol to Ketone Oxidation State 3.2 Alcohol to Acid Oxidation State 3.3 Olefin olefin (ō`ləfĭn) or olefin series: see alkene. olefin or alkene Any unsaturated hydrocarbon containing one or more pairs of carbon atoms linked by a double bond (see to Diol 3.4 Aldehyde aldehyde (ăl`dəhīd) [alcohol + New Lat. dehydrogenatus=dehydrogenated], any of a class of organic compounds that contain the carbonyl group, and in which the carbonyl group is bonded to at least one hydrogen; the general to Acid Oxidation State 3.5 Heteroatom het·er·o·at·om n. An atom other than carbon in the structure of a heterocyclic compound. Oxidations 4 Reductions 4.1 Alcohols to Alkanes The following is a list of straight-chain alkanes and their common names, sorted by number of carbon atoms. Number of C atoms Formula Common name Synonyms 1 CH4 Methane marsh gas; methyl hydride; natural gas 2 C2H6 4.2 Aldehydes, Amides, and Nitriles to Amines amines (  mēnz´),n.pl organic compounds that contain nitrogen. 4.3 Carboxylic Acids and Derivatives to Alcohols 4.4 Esters and Other Carboxylic Acid Derivatives to Aldehydes 4.5 Ketones Ketones Poisonous acidic chemicals produced by the body when fat instead of glucose is burned for energy. Breakdown of fat occurs when not enough insulin is present to channel glucose into body cells. Mentioned in: Diabetic Ketoacidosis, Urinalysis or Aldehydes to Alcohols 4.6 Ketones to Alkanes or Alkenes 4.7 Reductive Dehalogenations 4.8 Carbon-Carbon Double and Triple Bond Reductions 4.9 Heteroatom-Heteroatom Reductions 5 Carbon-Carbon Bond Formation 5.1 Carbon-Carbon Forming Reactions (Single Bonds) 5.2 Carbon-Carbon Double Bonds (Olefin Formation) 5.3 Reactions that Form Multiple Carbon-Carbon Bonds 6 Protecting Groups 6.1 Alcohols and Phenols 6.2 Amines and Anilines 6.3 Aldehydes and Ketones Index For more information visit http://www.researchandmarkets.com/reports/c81714 Source: Oxford University Press |
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