Millipore and Stem Cell Sciences Announce Agreement To Provide Human Embryonic Stem Cell Media.Breakthrough Product Will Provide Significant Advantages to Researchers Studying Human Embryonic Stem Cells Embryonic stem cells (ES cells) are stem cells derived from the inner cell mass of an early stage embryo known as a blastocyst. Human embryos reach the blastocyst stage 4-5 days post fertilization, at which time they consist of 50-150 cells. ES cells are pluripotent. BILLERICA, Mass. -- Millipore Corporation For other uses, see Millipore. Millipore Corporation (NYSE: MIL) founded in 1954, listed among the S&P 500 since the early 1990s, is an international biosciences company, known widely for its micrometer pore-size filters and tests. (NYSE NYSE See: New York Stock Exchange : MIL) and Stem Cell stem cell In living organisms, an undifferentiated cell that can produce other cells that eventually make up specialized tissues and organs. There are two major types of stem cells, embryonic and adult. Sciences (SCS) today announced an exclusive license for Millipore to develop and market SCS' serum free media for the growth of human embryonic stem cells (hESCs). The defined media will be the first product available in the industry that offers improved methods for growing hESCs without the need for animal serum. By eliminating the need for serum, researchers can generate improved experimental results by avoiding interference from animal products in the media, which will improve the ease of use and reliability in growing hESCs. The lack of animal-free, defined media for growing hESCs has been an important technical hurdle in enabling researchers to advance their understanding of the therapeutic value of stem cells stem cells, unspecialized human or animal cells that can produce mature specialized body cells and at the same time replicate themselves. Embryonic stem cells are derived from a blastocyst (the blastula typical of placental mammals; see embryo), which is very young . "Millipore is committed to being the most innovative supplier of products to the stem cell research market," said Dominique Baly, President of Millipore's Bioscience Division. "Our agreement with SCS reflects the significant investments we are making to serve the needs of researchers exploring the therapeutic value of stem cells. We chose SCS because their media worked extremely well in growing hESCs in a variety of different stem cell lines A stem cell line is a family of constantly-dividing cells, the product of a single parent group of stem cells. They are obtained from human or animal tissues and can replicate for long periods of time in vitro ("within glass"; or, commonly, "in the lab", in an artificial and conditions and they had the most advanced development of serum-free media." Under the terms of the agreement, Millipore will manufacture, market and sell the new media under the brand name HEScGRO Embryonic Stem Cell Medium. SCS will receive royalties from all future sales of HEScGRO Embryonic Stem Cell Medium. The agreement builds on the successful collaboration between Millipore and SCS formed in 2005 to commercialize media for the growth of mouse embryonic cells. Millipore's ESGRO Complete[TM] is the leading product used by researchers today for mouse stem cell experimentation. SCS Vice President and Chief Operating Officer Chief Operating Officer (COO) The officer of a firm responsible for day-to-day management, usually the president or an executive vice-president. , Hugh Ilyine said: "As researchers investigate using stem cells to create cures for new diseases, the use of hESCs are critical. By providing serum-free media to grow hESCs, scientists can be confident that the effects they are studying in the laboratory are from the cell itself and not from animal products in the media. The expansion of our agreement with Millipore will allow researchers to now benefit from products offering superior performance in both mouse and human stem cell research." Millipore expects to have HEScGRO Embryonic Stem Cell Medium available for commercial distribution before the end of the year. HEScGRO has been shown to be effective at growing many different human embryonic stem cell lines, including lines that have been approved by the U.S. government for use in federally sponsored research, as well as the "Mel" hES cell lines derived by Stem Cell Sciences in Australia and distributed by Millipore. Millipore offers a broad range of products and reagents for stem cell research through its Chemicon product line, which is part of the company's Research Reagents Business Unit. Millipore Research Reagents Business Unit creates innovative and high quality biological reagents for life science researchers to conduct their experiments consistently. These biological reagents include antibodies, dyes and biochemical reagents that are used to identify and measure cellular interactions, cell signaling Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as and other cellular functions. About Millipore Millipore is a leading provider of products and services that improve productivity in biopharmaceutical manufacturing and in clinical, analytical and research laboratories. The Company is organized in two operating divisions. Its Bioprocess bi·o·proc·ess n. 1. A technique that produces a biological material, such as a genetically engineered microbial strain, for commercial use. 2. Division helps to enable pharmaceutical and biotechnology companies Top 100 Biotechnology Companies The following is a list of the top 100 biotechnology companies ranked by revenue. The first nine companies qualify for the list of the top 50 pharmaceutical companies. to optimize their manufacturing productivity, ensure the quality of drugs, and scale up the production of difficult-to-manufacture biologics. Its Bioscience division helps to optimize laboratory productivity and workflows by providing reagents, kits and other enabling technologies and products for life science research and development. Millipore has a deep understanding of its customers' research and manufacturing process needs, and offers reliable and innovative tools, technologies and services. The Company is part of the S&P 500 Index and employs approximately 5,800 employees in more than 47 facilities worldwide. For additional information on Millipore Corporation, please visit its website at: www.millipore.com. About Stem Cell Sciences Stem Cell Sciences plc (SCS, AIM: STEM) is a global biotechnology company, established in Melbourne, Australia in 1994, providing products in the burgeoning stem cell research and drug discovery markets, in addition to the targeted development of cell-based therapies for neurodegenerative disease Neurodegenerative disease A disease in which the nervous system progressively and irreversibly deteriorates. Mentioned in: Amnesia and injury. The Company has established a leading intellectual property (IP) and technology portfolio that enables the commercial application of stem cells in drug discovery, providing the Company with early-stage revenue streams and technology development for at scale cell production of SCS cell-based therapeutics. SCS operates as a group of independent operations with laboratories in Scotland, Japan and Australia, each of which is affiliated with an academic centre of excellence. These include the Institute of Stem Cell Research (ISCR ISCR Investor Summit on Climate Risk ), Edinburgh, UK, RIKEN RIKEN Rikagaku Kenkyusho (Institute of Physical and Chemical Research, Japan) Centre for Development Biology, Kobe, Japan and the Australian Stem Cell Centre The Australian Stem Cell Centre - the National Biotechnology Centre of Excellence - is a research and development centre which focusses on regenerative medicine through the use of stem cells. It was founded in 2003, and has received over $100 million in funding in recent years. , Melbourne, Australia. For further information on the company please visit www.stemcellsciences.com. Forward Looking Statements: The matters discussed herein, as well as in future oral and written statements by management of Millipore Corporation that are forward-looking statements, are based on current management expectations that involve substantial risks and uncertainties which could cause actual results to differ materially from the results expressed in, or implied by, these forward-looking statements. Potential risks and uncertainties that could affect Millipore's future operating results include, without limitation, the inability to successfully integrate Serologicals or other acquired businesses, failure to achieve design wins into our pharmaceutical and biotechnology customers' manufacturing design phase for a particular drug; delay, suspension or termination of a customer's volume production; lack of availability of raw materials or component products on a timely basis; regulatory delay in the approval of new therapeutics; limitations on cash flow for operations and investment due to increased debt service obligations; the inability to establish and maintain necessary product and process quality levels; reduced demand for cell culture products using bovine serum; the inability to realize the expected benefits of development, marketing, licensing and other alliances; competitive factors such as new membrane or chromatography technology; the inability to achieve anticipated cost benefits of our supply chain initiative; risks relating to relating to relate prep → concernant relating to relate prep → bezüglich +gen, mit Bezug auf +acc our concentration of principal manufacturing operations Manufacturing operations concern the operation of a facility, as opposed to maintenance, supply and distribution, health, and safety, emergency response, human resources, security, information technology and other infrastructural support organizations. ; the inability to utilize technology in current or planned products due to overriding rights by third parties; potential environmental liabilities; conditions in the economy in general and in the bioscience and bioprocess markets in particular; foreign exchange fluctuations; reduced private and government research funding Research funding is a term generally covering any funding for scientific research, in the areas of both "hard" science and technology and social science. The term often connotes funding obtained through a competitive process, in which potential research projects are evaluated and ; exposure to product liability claims; and difficulties inherent in transferring or outsourcing of manufacturing operations. Please refer to our filings with the SEC, including our most recent Annual Report on Form 10-K Form 10-K A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information. Form 10-K See 10-K. , for more information on these and other risks that could cause actual results to differ. |
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