Millipore Corporation and Applied Biosystems Introduce New MALDIspot Kit; Expected to Accelerate MALDI MS Sample Preparation.To download high-resolution, print-ready JPEG JPEG in full Joint Photographic Experts Group Standard computer file format for storing graphic images in a compressed form for general use. JPEG images are compressed using a mathematical algorithm. images, click on the thumbnail image above. WARNING: these images are very large (800K+) Click here for caption Business Editors/Health/Medical Writers NOTE TO MEDIA: Multimedia assets available A photo is available at URL URL in full Uniform Resource Locator Address of a resource on the Internet. The resource can be any type of file stored on a server, such as a Web page, a text file, a graphics file, or an application program. : http://www.businesswire.com/cgi-bin/photo.cgi?pw.062303/bb8 BILLERICA, Mass. & FOSTER CITY, Calif.--(BUSINESS WIRE)--June 23, 2003 Millipore Corporation For other uses, see Millipore. Millipore Corporation (NYSE: MIL) founded in 1954, listed among the S&P 500 since the early 1990s, is an international biosciences company, known widely for its micrometer pore-size filters and tests. (NYSE NYSE See: New York Stock Exchange : MIL) and Applied Biosystems (NYSE: ABI Abi (ā`bī) [short for Abijah], in the Bible, King Hezekiah's mother. (Application Binary Interface) A specification for a specific hardware platform combined with the operating system. ), an Applera Corporation business, today announced the availability of the MALDIspot(TM) Kit, which is expected to improve the sensitivity of mass spectrometry mass spectrometry or mass spectroscopy Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields. (MS) by maximizing peptide recovery during sample preparation of gel spots. The kit is the second in a series of MS sample preparation products being developed through a proteomics partnership between Millipore and Applied Biosystems. The MALDIspot Kit includes the new ZipPlate(R) micro-SPE plate, the first 96-well sample preparation tool for destaining, digesting, and concentrating proteins from either 1D or 2D gels in a single plate. Also included is an apparatus that allows direct elution elution /elu·tion/ (e-loo´shun) in chemistry, separation of material by washing; the process of pulverizing substances and mixing them with water in order to separate the heavier constituents, which settle out in solution, from the of purified peptides onto an Applied Biosystems MALDI MALDI Matrix-Assisted Laser Desorption/Ionization target insert in a matrix solution of only 1-2 uL. The insert is then placed into a sled, which is compatible with all Voyager-DE(TM) workstations, as well as the QSTAR QSTAR Quantitative Structure-Time-Activity Relationships (R) XL Hybrid LC/MS/MS System with oMALDI(TM) source. Additional kit components include Applied Biosystems MALDI target inserts, a vacuum manifold adapter, sled, and cleaning solution. By eliminating all sample transfer steps, the MALDIspot Kit is expected to maximize sample recovery, allow detection of lower abundance proteins in gels, and accelerate the entire process. With ZipPlate devices, 8-96 samples can be processed in just seven hours, more than twice as fast as the 16 hours that traditional methods require. The device is configured for manual or automated use. Automation protocols are available from Millipore. For more information, contact Millipore Tech Service at 1-800-MILLIPORE or visit www.millipore.com/maldispot. About Millipore Millipore is a multinational bioscience company that provides technologies, tools and services for the discovery, development and production of new therapeutic drugs. It serves the life science research, biotechnology and pharmaceutical industries. For more information about Millipore visit www.millipore.com. Millipore Forward Looking Statement Disclaimer The matters discussed herein, as well as in future oral and written statements by management of Millipore Corporation that are forward-looking statements, are based on current management expectations that involve substantial risks and uncertainties which could cause actual results to differ materially from the results expressed in, or implied by, these forward-looking statements. Potential risks and uncertainties that could affect Millipore's future operating results include, without limitation, foreign exchange rates; regulatory delay in the approval of new therapeutics; further consolidation of drug manufacturers; competitive factors such as new membrane technology; lack of availability of raw materials or component products on a timely basis; inventory risks due to shifts in market demand; change in product mix; conditions in the economy in general and in the bioscience markets in particular; potential environmental liabilities; the inability to utilize technology in current or planned products due to overriding rights by third parties; difficulties inherent in research and development activities; and the risk factors listed from time to time in Millipore's filings with the SEC. About Applera Corporation and Applied Biosystems Applera Corporation comprises two operating groups. The Applied Biosystems Group develops and markets instrument-based systems, reagents, software, and contract services to the life science industry and research community. Customers use these tools to analyze nucleic acids Nucleic acids The cellular molecules DNA and RNA that act as coded instructions for the production of proteins and are copied for transmission of inherited traits. (DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. and RNA RNA: see nucleic acid. RNA in full ribonucleic acid One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic ), small molecules, and proteins to make scientific discoveries, develop new pharmaceuticals, and conduct standardized testing. Applied Biosystems is headquartered in Foster City, CA, and reported sales of $1.6 billion during fiscal 2002. The Celera Genomics Group (NYSE: CRA See Community Reinvestment Act. ), located in Rockville, MD, and South San Francisco South San Francisco, city (1990 pop. 54,312), San Mateo co., W Calif.; inc. 1908. South San Francisco has several industrial parks; its manufactures include medical supplies and equipment, foods, paint, paper products, consumer goods, and clothing. , CA, is engaged principally in integrating advanced technologies to discover and develop new therapeutics. Celera intends to leverage its proteomic, bioinformatic, and genomic capabilities to identify and validate drug targets, and to discover and develop new therapeutics. Its Celera Discovery System(TM) online platform, marketed exclusively through the Applied Biosystems Knowledge Business, is an integrated source of information based on the human genome and other biological and medical sources. Celera Diagnostics, a 50/50 joint venture between Applied Biosystems and Celera Genomics, is focused on discovery, development, and commercialization of novel diagnostic products. Information about Applera Corporation, including reports and other information filed by the company with the Securities and Exchange Commission, is available at http://www.applera.com, or by telephoning 800.762.6923. Information about Applied Biosystems is available at http://www.appliedbiosystems.com. Certain statements in this press release are forward-looking. These may be identified by the use of forward-looking words or phrases such as "expect" among others. These forward-looking statements are based on Applera Corporation's current expectations. The Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995 provides a "safe harbor Safe Harbor 1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated. 2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive. " for such forward-looking statements. In order to comply with the terms of the safe harbor, Applera Corporation notes that a variety of factors could cause actual results and experience to differ materially from the anticipated results or other expectations expressed in such forward-looking statements. These factors include but are not limited to (1) rapidly changing technology and dependence on development of new products; (2) Applied Biosystems' sales are dependent on customers' capital spending capital spending Spending for long-term assets such as factories, equipment, machinery, and buildings that permits the production of more goods and services in future years. policies and government-sponsored research; (3) Applied Biosystems' significant overseas operations, with attendant exposure to fluctuations in the value of foreign currencies; and (4) other factors that might be described from time to time in Applera Corporation's filings with the Securities and Exchange Commission. All information in this press release is as of the date of the release, and Applera does not undertake any duty to update this information, including any forward-looking statements, unless required by law. (C) 2003 Applera Corporation and Millipore Corporation. All rights reserved. For Research Use Only. Not for use in diagnostic procedures. Applied Biosystems and QSTAR are registered trademarks and Applera, Celera, Celera Diagnostics, Celera Discovery System, Celera Genomics, oMALDI, and Voyager-DE are trademarks of Applera Corporation and/or its subsidiaries in the US and certain other countries. Millipore and ZipPlate are registered trademarks and MALDIspot is a trademark of Millipore Corporation. Note: A photo is available at URL: http://www.businesswire.com/cgi-bin/photo.cgi?pw.062303/bb8 |
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