MathSoft Announces S+SeqTrial Software for Design of Clinical Trials; Powerful Software Helps To Bring Beneficial Drugs To Market Faster.Business Editors SEATTLE--(BUSINESS WIRE)--March 2, 2000 MathSoft, Inc. (Nasdaq:MATH), provider of the broadest line of technical calculation and analytical software Analytical software is software that is designed specifically for and development of a particular environment or object. for business and academia, today introduced S+SeqTrial(R), the latest addition to the S-PLUS product family. The FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. has recently been under increasing pressure from political and special interest groups to bring beneficial drugs to market sooner. S+SeqTrial software helps leading biostatisticians developing new pharmaceutical products to evaluate and monitor clinical trials more efficiently and effectively. Each year, the global pharmaceutical industry spends at least $10 billion on clinical trials. Software packages such as S+SeqTrial have the potential to save the industry hundreds of millions of dollars by improving clinical trial efficiency, reducing the number of human subjects required, and limiting scarce research resources. "S+SeqTrial is the perfect tool for designing and monitoring clinical trials including a comprehensive selection of validated designs integrated with powerful data analysis capabilities," says Gracie Liebermann, biostatistician, Genentech. "Its easy-to-use graphical user interface graphical user interface (GUI) Computer display format that allows the user to select commands, call up files, start programs, and do other routine tasks by using a mouse to point to pictorial symbols (icons) or lists of menu choices on the screen as opposed to having to and professional graphics are ideal for communicating results to non-statisticians and FDA reporting. S+SeqTrial will help our company to make decisions to terminate or continue trials sooner, potentially saving lives and reducing clinical trial costs." The specialized software, designed for clinicians and researchers, delivers efficiencies in clinical trial design, monitoring, and data analysis in a single computing computing - computer environment. S+SeqTrial offers a flexible toolkit for selecting an appropriate clinical design. Biostatisticians can explore trial design tradeoffs from different interest groups including: the FDA, Data Safety Monitoring Safety Monitoring of a clinical trial is conducted by an independent physician with relevant expertise. This is accomplished by review of adverse event, immediately after they occur, with timely follow-up through resolution. Board (DSMB DSMB Data & Safety Monitoring Board Clinical research A committee of independent clinical research experts who review data in ongoing clinical trials, ensuring that participants are not exposed to undue risk, and look for any differences in effectiveness ), business planners, and biostatisticians. The software uses monitoring and data analysis within a group sequential design to determine whether or not a study should continue. Biostatisticians can evaluate data on an ongoing basis and perform interim analyses about drug efficacy earlier, saving valuable time and money. S+SeqTrial offers sophisticated data analysis using S-PLUS. From drug discovery to new drug application preparation, S-PLUS software provides a powerful data analysis tool for the pharmaceutical and biotech bi·o·tech n. Informal Biotechnology. biotech Noun short for biotechnology Noun 1. industries. "S+SeqTrial is designed to meet the needs of leading biostatisticians and clinicians," says Shawn Javid, senior vice president and general manager, MathSoft Inc. "We are excited to deliver innovative design and monitoring software to the pharmaceutical industry. The software provides biostatisticians with the versatility and functionality they need to bring effective treatments to market faster while satisfying ethical concerns for patient safety by stopping trials of ineffective or unsafe treatments sooner." Key features and benefits of S+SeqTrial include: -- Easy-to-Use, Powerful Design--S+SeqTrial is an easy-to-use software package designed to evaluate clinical design and monitor data collection on an ongoing basis. The software offers a complete toolkit for evaluation of designs. Its familiar graphical user interface includes a customized toolbar A toolbar that can be custom configured by the user. Buttons can be added and deleted as required. and comparative plots of boundaries, power curves, average sample number (ASN (1) (Autonomous System Number) A unique identifier of an autonomous system on the Internet. Of the 65 thousand ASNs available, more than 30 thousand have been assigned to ISPs and NSPs. ISPs usually have only one ASN, but NSPs may have more than one. ), stopping probabilities, and more. Flexible monitoring schedules and exact inference (logic) inference - The logical process by which new facts are derived from known facts by the application of inference rules. See also symbolic inference, type inference. capabilities make this package ideal for leading biostatisticians. -- Fully Object-Oriented Language--Users can conveniently update, modify and plot design objects. -- Specialized Analysis--The module offers various low-level routines including densities, quantiles, and distribution functions for group sequential test statistics. -- Integrated with S-PLUS--With S+SeqTrial, users can take advantage of the full range of statistical and interactive graphical tools in S-PLUS for customized analysis to extend S+SeqTrial as applications demand. AVAILABILITY S+SeqTrial is available in stand alone licensed or network versions for Windows 95/98/NT Refers to all 32-bit versions of Windows prior to Windows 2000. It implies Windows ME and Windows 2000. It specifically excludes Windows 3.x. See Windows. commercially. Academic, non-profit and government pricing is also available. ABOUT S MathSoft's data analysis product family, which includes S-PLUS and MathSoft StatServer(R), is based on S, an object-oriented language object-oriented language - object-oriented programming developed at Lucent Technologies specifically for data visualization See information visualization. , exploration and programming with data. S provides a rich, object-oriented environment designed for interactive data discovery. With a huge library of functions for all aspects of computing with data, S offers unmatched power, flexibility and extensibility. The S System was recently honored with the prestigious Software Systems Award given by the Association for Computing Machinery See ACM. Association for Computing Machinery - Association for Computing . Other hallmark technologies recognized with this award include UNIX UNIX Operating system for digital computers, developed by Ken Thompson of Bell Laboratories in 1969. It was initially designed for a single user (the name was a pun on the earlier operating system Multics). , TCP/IP TCP/IP in full Transmission Control Protocol/Internet Protocol Standard Internet communications protocols that allow digital computers to communicate over long distances. , Tcl/Tk, INGRES, and Mosaic. MathSoft has exclusive worldwide rights to develop and distribute products incorporating the S technology. ABOUT MATHSOFT Founded in 1984, MathSoft is the provider of the broadest line of technical calculation and analytical software for business and academia. With MathSoft's products, users can deploy technical calculations and exploratory data analyses across their entire organizations. The company has more than 1.3 million users of its Mathcad(R), StudyWorks(R), S-PLUS(R), StatServer(R) and Axum(R) software worldwide. Users include technical professionals worldwide at more than 90% of the Fortune 1,000 companies and over 500 government installations, and students and faculty at over 2,000 colleges and universities. FreeScholarships.com, Inc., www.freescholarships.com, a subsidiary of MathSoft, Inc., helps families and students meet the rising costs of education by giving away money for school in daily online drawings and auctions. Founded in 1999, the site provides information on schools, funding, and careers, while serving as an entertainment, shopping, and community center for visitors of all ages. S-PLUS product information can be obtained via MathSoft's Web site located at http://www.splus.mathsoft.com,by phone at 1-800/569-0123, by fax at 206/283-8691 or via mail at 1700 Westlake Avenue North, Suite 500, Seattle, WA 98109. MathSoft's corporate headquarters can be reached by phone at 1-800/628-4223, by fax at 617/577-8829 or via mail at 101 Main Street, Cambridge, MA 02142. Axum, Mathcad, StudyWorks, S-PLUS and StatServer are registered trademarks and the MathSoft logo is a trademark of MathSoft, Inc. Other product and service names mentioned are the property of their respective owners. |
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