MIV Therapeutics to Unveil Technologies Targeting $23 Billion Orthopedics Device Market; Company Announces Broader Applications for Proprietary Biocompatible HAp Coating Technologies to Improve Hip, Knee and Spinal Implants.ATLANTA -- MIV MIV Motorisierter Individualverkehr (German: Motorized Individual Traffic) MIV Master Internet Volunteer (University of Minnesota Extension Service) MIV Multimedia, Internet & Video Therapeutics (OTCBB OTCBB See OTC Bulletin Board (OTCBB). :MIVT MIVT Mechanism, Injuries, Vital Signs, Treatment (trauma reporting) ) (FWB (Fixed Wireless Broadband) See fixed wireless. :MIV), a leading developer of next-generation biocompatible biocompatible /bio·com·pat·i·ble/ (-kom-pat´i-b'l) being harmonious with life; not having toxic or injurious effects on biological function. coatings and advanced drug delivery systems for cardiovascular stents and other implantable medical devices, will unveil technology to address multiple revenue opportunities in the $23 billion orthopedic device market at the upcoming World Orthopedic Organization (SICOT SICOT Société Internationale de Chirurgie Orthopédique et de Traumatologie (International Society of Orthopaedic Surgery and Traumatology) ) conference in Buenos Aires, later this month. MIVT is developing a new generation of coating applications based on Hydroxyapatite hydroxyapatite /hy·droxy·ap·a·tite/ (-ap´ah-tit) an inorganic calcium-containing constituent of bone matrix and teeth, imparting rigidity to these structures. (HAp), an organically derived substance, well known and widely used in dentistry and orthopedics. The Company's proprietary HAp-based drug delivery nano- and micro-technology is well suited for use as a therapeutic coating for a variety of orthopedic implants. "The orthopedic market represents an enormous opportunity for MIVT and is a natural extension of our R&D program," said Dr. Mark Landy, President of MIVT. "We believe our proprietary HAp technologies will significantly improve patient outcomes when compared to current solutions, in both cardiology and orthopedics." Dr. Tom Troczynski, Ph.D, Vice President of Coating Technologies of MIVT, will for the first time present the Company's R&D progress in orthopedics, at the upcoming World Orthopedic Organization (SICOT) conference in Buenos Aires, on August 24, 2006. "While HAp is known to improve the integration of hip and knee implants with bone, particularly in the critical early several-week period after implantation, MIVT's proprietary drug-carrying coatings may provide further significant impact on post-implant success rates," said Dr. Troczynski. "MIVT's nano-drug-elution technology may have significant impact on implantation protocols, and post-implantation success rate for patients receiving hip and knee implants, as well as spinal devices." According to industry analysts, the 2006 orthopedic device market will total an estimated $23.2 billion worldwide. MIVT's technologies address products used in the reconstructive and spinal segments of this market, representing approximately $16 billion. MIVT's HAp-based biocompatible coatings are designed to substantially improve the safety and long-term performance of vascular stents and other devices because they do not trigger adverse reactions adverse reactions, n.pl unfavorable reactions resulting from administration of a local anesthetic; responsible factors include the drug used, concentration, and route of administration. of the body's immune system. Such complications include inflammation, creation of thrombus thrombus /throm·bus/ (throm´bus) pl. throm´bi a stationary blood clot along the wall of a blood vessel, frequently causing vascular obstruction. (blood clots) and, in the case of vascular stents, re-narrowing of arteries, called restenosis, due to endothelial endothelial /en·do·the·li·al/ (-the´le-al) pertaining to or made up of endothelium. Endothelial A layer of cells that lines the inside of certain body cavities, for example, blood vessels. tissue re-growth inside blood vessels in the area of newly implanted stents. SICOT is an international not-for-profit association incorporated under Belgian law with the aim to advance the science and art of orthopedics and traumatology traumatology /trau·ma·tol·o·gy/ (-tol´o-je) the branch of surgery dealing with wounds and disability from injuries. trau·ma·tol·o·gy n. at an international level and to foster and develop teaching, research and education. In September 2005 it celebrated its 75th anniversary. About SICOT: The World Orthopedic Organization SICOT is an international not-for-profit association incorporated under Belgian law with the aim to advance the science and art of orthopedics and traumatology at an international level and to foster and develop teaching, research and education. It is the only truly global society of orthopedic surgeons with some 3,000 members from more than 100 countries around the world. For more information, visit www.sicot.org. About MIV Therapeutics Inc. MIV Therapeutics is developing a next-generation line of advanced biocompatible coatings for passive and drug-eluting applications on cardiovascular stents and a broad range of other implantable medical devices. The Company's ultra-thin coating formulation is designed to protect surrounding tissue from potentially harmful interactions with bare metallic stents. The Company's unique ultra-thin coating platform is derived from an organic material called hydroxyapatite (HAp) which has demonstrated excellent safety and biocompatibility biocompatibility the quality of not having toxic or injurious effects on biological systems. biocompatibility 1. The extent to which a foreign, usually implanted, material elicits an immune or other response in a recipient 2. in vivo animal studies. Hydroxyapatite is a bioactive porous material that makes up the bone mineral and matrix of teeth and is widely used today as a bone substitute material and for coatings on implantable fixation devices in orthopedic, dental and other applications. The Company's novel polymer-free drug eluting technologies based on Hydroxyapatite could also provide an attractive alternative to current polymer-based drug eluting coatings on the stent market, which have been associated with undesirable medical effects. The Company's drug eluting coatings are additionally designed to suit a broad range of implantable medical devices that could benefit from highly customizable drug release profiles. MIVT has a Collaborative Research Agreement (CRA See Community Reinvestment Act. ) with the University of British Columbia Locations Vancouver The Vancouver campus is located at Point Grey, a twenty-minute drive from downtown Vancouver. It is near several beaches and has views of the North Shore mountains. The 7. and has received Government grant for its research program on the "Development of Novel Drug Eluting Composite Coatings for Cardiovascular Stents," under the National Research Council-Industrial Research Assistance Program (NRC-IRAP NRC-IRAP National Research Council - Industrial Research Assistance Program ). Under this sponsorship, the Company is expected to complete its drug-eluting research and development program and to reach product commercialization stage. For more information, please visit http://www.trilogycapital.com/tcp/mivt/website.html. To read or download MIV Therapeutics' Investor Fact Sheet, visit http://www.trilogy-capital.com/tcp/mivt/factsheet.html. To obtain daily and historical Company stock quote data, and recent Company news releases, visit http://www.trilogy-capital.com/tcp/html/mivt.htm. MIVT is traded on the Frankfurt, Germany, stock exchange under the symbol MIV. Forward-Looking Statements Except for the historical information contained herein, the matters discussed in this press release are forward-looking statements. Such statements are indicated by words or phrases such as "believe," "will," "breakthrough," "significant," "indicated," "feel," "revolutionary," "should," "ideal," "extremely" and "excited." These statements are made under "Safe Harbor" provisions of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995. Actual results may differ materially from those described in forward-looking statements and are subject to risks and uncertainties. See the Company's filings with the Securities and Exchange Commission including, without limitation, the Company's recent Form 10-K and Form 10-Qs, which identify specific factors that may cause actual results or events to differ materially from those described in the forward-looking statements. |
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