MIV Therapeutics Releases CEO Letter to Shareholders Highlighting Recent Strategic Achievements and Progress.CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. Cites Recent Milestone Agreement to Acquire China-Based Vascore Medical and India-Based Biosync Scientific to Accelerate Commercialization of Next Generation Stent stent (stent) 1. a device or mold of a suitable material, used to hold a skin graft in place. 2. a slender rodlike or threadlike device used to provide support for tubular structures that are being anastomosed, or Technology ATLANTA -- MIV MIV Motorisierter Individualverkehr (German: Motorized Individual Traffic) MIV Master Internet Volunteer (University of Minnesota Extension Service) MIV Multimedia, Internet & Video Therapeutics Inc. (OTCBB OTCBB See OTC Bulletin Board (OTCBB). :MIVT MIVT Mechanism, Injuries, Vital Signs, Treatment (trauma reporting) ) (FWB (Fixed Wireless Broadband) See fixed wireless. :MIV), a leading developer of next-generation biocompatible biocompatible /bio·com·pat·i·ble/ (-kom-pat´i-b'l) being harmonious with life; not having toxic or injurious effects on biological function. coatings and advanced drug delivery systems for cardiovascular stents and other implantable medical devices, today announced that Chairman and Chief Executive Officer, Alan P. Lindsay, has released a letter to shareholders, in which he reviews the most recent material developments, including recent agreements to acquire China-based Vascore Medical and India-based Biosync Scientific. Other milestone achievements include the Company's recently announced intention to begin human implantation implantation /im·plan·ta·tion/ (im?plan-ta´shun) 1. attachment of the blastocyst to the epithelial lining of the uterus, its penetration through the epithelium, and, in humans, its embedding in the stratum compactum of the of its biocompatible stent coating technology early this year. Dear Shareholders, 2006 was a banner year for MIV Therapeutics. We were proud to be included in the "NANOTECH Top 100," presented by the International Association of Nanotechnology (IAnano) and FORTUNE Magazine featuring the leading 100 public nanotech companies worldwide, another public acknowledgment of the importance MIVT's advanced technology and development programs. The article was published in the FORTUNE 500 2006 issue in April. Since then we have continued to make significant strategic progress, highlighted by two formal acquisition agreements that will give us a sizeable footprint in the fast growing Chinese and Indian markets. These transactions will give us a broad product portfolio and add to a deep pipeline of breakthrough technologies. We were pleased to welcome Dr. Mark Landy, a nationally ranked Wall Street medical device analyst and industry authority, joined MIVT as President. Dr. Landy is a well-known pundit An expert or knowledgeable person. From "pandit" in Hindi. See guru. in the financial media who has made frequent appearances on CNBC CNBC Center for the Neural Basis of Cognition (artificial intelligence) CNBC Consumer News and Business Channel CNBC Congress of National Black Churches, Inc. , Reuters, Dow Jones Dow Jones the best known of several U.S. indexes of movements in price on Wall Street. [Am. Hist.: Payton, 202] See : Finance , Bloomberg, The Wall Street Journal and Business Week, to name a few, and has already brought vast experience, knowledge and pedigreed relationships to MIVT. Our technology progressed significantly and we added some tremendous talent to our research and development teams and some of the most respected minds in cardiology cardiology Medical specialty dealing with heart diseases and disorders. It began with the 1749 publication by Jean Baptiste de Sénac of contemporary knowledge of the heart. Diagnostic methods improved in the 19th century, and in 1905 the electrocardiograph was invented. to our Scientific Advisory Board. These efforts culminated in the very successful trial programs we ran during the year, with final results indicating that our polymer-free HAp technology is at least as good and in some cases better than Johnson & Johnson's Cypher See cipher. stent, and have paved the way for first human implantation planned for early this year. The emphasis on producing a new generation polymer-free drug eluting stent is growing by the day. The industry received significant scrutiny after some study results suggest that current polymer-coated versions of the DES stents are risky for some patients and could be the cause of late thrombosis thrombosis (thrŏmbō`sĭs), obstruction of an artery or vein by a blood clot (thrombus). Arterial thrombosis is generally more serious because the supply of oxygen and nutrition to an area of the body is halted. (blood clot blood clot n. A semisolid, gelatinous mass of coagulated blood that consists of red blood cells, white blood cells, and platelets in a fibrin network. ) with potentially deadly results. As I mentioned, MIVT has made great progress in its strategy to acquire interests and companies involved in advanced stent technology. In September, we agreed to acquire China-based Vascore Medical, which is expected to provide MIVT with extensive design, manufacturing and marketing capabilities. And in December, we executed an agreement to acquire Biosync Scientific, a leading Indian interventional cardiology interventional cardiology Cardiology The subspecialty of cardiology dedicated to the diagnosis, medical and mechanical therapy, pre- and post-procedure management of adult patients with acute and chronic forms of cardiovascular disease amenable to catheter-based company that designs and develops innovative products, including cardiovascular stents. Through the Biosync acquisition agreement, MIVT will receive seven newly announced products that have already received CE Mark certification, all of which are now available for sale in CE Mark jurisdictions world wide. The transactions will accelerate our commercialization process and bring MIVT many key design, production, sales and distribution capabilities and an important presence in some of the world's fastest growing economies and markets. Our recently announced financing will allow us to execute those agreements and prepare for initial human testing planned for early 2007 and to further develop the sales, marketing and distribution of the CE marked products in India, China and fields abroad. Below are some of our more significant headlines from 2006. The company issued over 33 press releases during the year and all the details can be found on our website, www.mivtherapeutics.com. Jan 8, 2007: MIV Therapeutics Executes Private Financings for $4 Million to Support Acquisitions, Development and Distribution of Next Generation Stents Dec 14, 2006: MIV Therapeutics Announces Market Launch of the GenX CrCo Stent and Seven Associated Interventional Cardiology Products by Biosync Scientific Dec 11, 2006: MIV Therapeutics Executes Milestone Agreement to Acquire Biosync Scientific, a Leading Indian Interventional Cardiology Company. Acquisition Provides MIVT with Highly Competitive CE Marked Bare Metal Stent Platform Nov 29, 2006: MIV Therapeutics Announces Company's Biocompatible Stents Matches or Outperforms World's Leading Drug-Eluting Stent in Key Categories. Excellent Results from Preclinical Study of Biocompatible Polymer-Free Drug Eluting Stent Coating Technologies Paves the Way Towards Human Trials. Oct 27, 2006: MIV Therapeutics Announces Timeline for First Human Implantation of HAp NanoFilm Coated Stent MIV Therapeutics, a leading developer of next-generation biocompatible drug-eluting stents, announced today that it intends to begin the first human implants of a HAp NanoFilm coated stent early in 2007 Oct 23, 2006: MIV Therapeutics to Detail Research Results Showing Excellent Performance of Breakthrough Stent Coatings at TCT Conference Sep 21, 2006: MIV Therapeutics Appoints Montreal Heart Institute Interventional Cardiologist Dr. Raoul Bonan to Guide Clinical Programs. Sep 15, 2006: MIV Therapeutics Appoints Mid-America Heart Institute Director Dr. David Cohen to Scientific Advisory Board; Respected Interventional Cardiologist to Assist Commercialization of MIVT Technologies for Safer Cardiovascular Stents Sep 14, 2006: MIV Therapeutics Names Harvard Interventional Cardiologist Dr. Joseph Carrozza to Scientific Advisory Board; Industry Authority to Help Guide Development of MIVT's Unique Coatings for Highly Biocompatible Cardiovascular Stents Sep 13, 2006: MIV Therapeutics Enters into Formal Agreement to Acquire Vascore Medical Co. Ltd.; a Leading Chinese Manufacturer of Advanced Cardiovascular Stents Aug 25, 2006: MIV Therapeutics Subsidiary Invited to Present Groundbreaking Stroke-Prevention Device at Top International Symposium. SagaX to Spotlight Latest Developments to Commercialize Unique Implantable Embolic Filter at TCT2006 Conference Jul 6, 2006: MIVT Cites Growing Body of Scientific Evidence Validating Company's Strategy to Create Safer, Better Cardiovascular Stents. Company's Proprietary Solutions to Address Widespread Medical Concerns Detailed in Wall Street Journal, JAMA Jun 5, 2006: MIV Therapeutics' Breakthrough Vascular Stent Coating Technology Receives Key Independent Endorsement in New Scientific Study. Independent Research Confirms Primary Safety and Biocompatibility Attributes of Company's Patented HAp Coatings. May 8, 2006: MIV Therapeutics Highlights HAp Composite Coating Technologies at Leading Conference on Biomaterials. Better, Safer, More Biocompatible Stent Coating Technologies Presented at Recent International Society of Biomaterials Meeting Apr 18, 2006: MIV Therapeutics Named to Top 100 Nanotechnology Companies by International Association of Nanotechnology. Developer of Novel Biomedical Coatings Developer in Same Top 100 List as Major Wall St. and Fortune 500 Companies Apr 4, 2006: MIV Therapeutics Appoints Nationally Ranked Wall Street Medical Device Analyst and Industry Authority Mark Landy as President. Landy to Bring Strong Institutional Investment and Business Development Background Apr 10, 2006: MIV Therapeutics' Bio-compatible Medical Coating Technologies Featured in Fortune 500 Nanotechnology Special Report. Business Magazine Spotlights MIVT's Plan to Commercialize Proprietary Device Coatings for $160 Billion Drug Delivery Marketplace Mar 22, 2006: MIVT New Patent Application Targets Worldwide Demand for Safer Drug Delivery Solutions for Chronic Diseases. New Non-Polymeric Drug-Eluting Coatings Offer High Biocompatibility, Drug Storage and Controlled Drug Release Mar 9, 2006: MIV Therapeutics SagaX Subsidiary Announces Appointment of New Executives and Technology Specialists. Additions to Sagax Team Strengthens Management and Accelerates Development of Novel Stroke Prevention Device. Mar 2, 2006: MIVT Invited to Lecture on its Proprietary Biocompatible Coatings for Implanted Medical Devices and Drug Delivery Systems for the Localized Treatment of Diseases Feb 10, 2006: MIV Therapeutics Hires Noted Pharmacology Scientist Dr. Vlad Budzynski to Direct Multiplatform Drug Delivery Program. Veteran Researcher and University Professor Brings Expertise in Drug Development and Advanced Biomedical Solutions As you can see, MIVT is firmly committed to continue building shareholder value. Our management team is determined to deliver our next generation medical devices to the interventional cardiac market and to improve the lives of those patients whom it benefits. I invite you to continue following MIVT's extraordinary success. Thank you for your time and support. Regards, Alan P. Lindsay, Chairman and Chief Executive Officer About MIV Therapeutics, Inc. MIV Therapeutics is developing a next-generation line of advanced biocompatible coatings for passive and drug-eluting applications on cardiovascular stents and a broad range of other implantable medical devices. The Company's ultra-thin coating formulation is designed to protect surrounding tissue from potentially harmful interactions with bare metallic stents. The Company's unique ultra-thin coating platform is derived from an organic material called hydroxyapatite hydroxyapatite /hy·droxy·ap·a·tite/ (-ap´ah-tit) an inorganic calcium-containing constituent of bone matrix and teeth, imparting rigidity to these structures. (HAp) which has demonstrated excellent safety and biocompatibility biocompatibility the quality of not having toxic or injurious effects on biological systems. biocompatibility 1. The extent to which a foreign, usually implanted, material elicits an immune or other response in a recipient 2. in vivo in vivo /in vi·vo/ (ve´vo) [L.] within the living body. in vi·vo adj. Within a living organism. in vivo adv. animal studies. Hydroxyapatite is a bioactive bi·o·ac·tive adj. Of or relating to a substance that has an effect on living tissue. bioactive having an effect on or eliciting a response from living tissue. porous material that makes up the bone mineral and matrix of teeth and is widely used today as a bone substitute material and for coatings on implantable fixation devices in orthopedic, dental and other applications. The Company's novel polymer-free drug-eluting technologies based on Hydroxyapatite could also provide an attractive alternative to current polymer-based drug-eluting coatings on the stent market, which have been associated with undesirable medical effects. The Company's drug-eluting coatings are additionally designed to suit a broad range of implantable medical devices that could benefit from highly customizable drug release profiles. MIVT has a Collaborative Research Agreement (CRA See Community Reinvestment Act. ) with the University of British Columbia Locations Vancouver The Vancouver campus is located at Point Grey, a twenty-minute drive from downtown Vancouver. It is near several beaches and has views of the North Shore mountains. The 7. and has received Government grant for its research program on the "Development of Novel Drug Eluting Composite Coatings for Cardiovascular Stents," under the National Research Council-Industrial Research Assistance Program (NRC-IRAP NRC-IRAP National Research Council - Industrial Research Assistance Program ). Under this sponsorship, the Company is expected to complete its drug-eluting research and development program and to reach product commercialization stage. For more information, please visit http://www.trilogy-capital.com/tcp/mivt/website.html. To read or download MIV Therapeutics' Investor Fact Sheet, visit http://www.trilogy-capital.com/tcp/mivt/factsheet.html. To obtain daily and historical Company stock quote data, and recent Company news releases, visit http://www.trilogy-capital.com/tcp/html/mivt.htm. MIVT is traded on the Frankfurt, Germany, stock exchange under the symbol MIV. Forward-Looking Statements forward-looking statement A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections. Except for the historical information contained herein, the matters discussed in this press release are forward-looking statements. Such statements are indicated by words or phrases such as "believe," "will," "breakthrough," "significant," "indicated," "feel," "revolutionary," "should," "ideal," "extremely" and "excited." These statements are made under "Safe Harbor Safe Harbor 1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated. 2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive. " provisions of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995. Actual results may differ materially from those described in forward-looking statements and are subject to risks and uncertainties. See the Company's filings with the Securities and Exchange Commission including, without limitation, the Company's recent Form 10-K Form 10-K A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information. Form 10-K See 10-K. and Form 10-Qs Form 10-Q See 10-Q. , which identify specific factors that may cause actual results or events to differ materially from those described in the forward-looking statements. |
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