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MIV Therapeutics' Intellectual Property Portfolio Expands to 43 Patents, Patent Applications and Licenses on Novel Technologies; Aggressive IP Protection of Coating Technologies Positions Company for Entry into $100 Billion Drug-Delivery Market.


VANCOUVER, British Columbia -- MIV MIV Motorisierter Individualverkehr (German: Motorized Individual Traffic)
MIV Master Internet Volunteer (University of Minnesota Extension Service)
MIV Multimedia, Internet & Video
 Therapeutics, Inc. (OTCBB OTCBB

See OTC Bulletin Board (OTCBB).
:MIVT MIVT Mechanism, Injuries, Vital Signs, Treatment (trauma reporting) ) (Frankfurt/FSE:MIV), a developer of next-generation biocompatible biocompatible /bio·com·pat·i·ble/ (-kom-pat´i-b'l) being harmonious with life; not having toxic or injurious effects on biological function.  passive and drug-eluting stent coatings and drug delivery technologies for the treatment of cardiovascular disease, has announced that its intellectual property portfolio has achieved a total of 43 U.S. and international patents and patent applications. Aggressive steps taken to secure patent protection for the IP portfolio reflect the Company's vision and business strategy to generate significant revenues from its proprietary coating solutions, targeting the projected $100 billion dollar global marketplace for coronary stents and advanced drug-delivery systems.

The Company's intellectual property portfolio includes patents held by the University of British Columbia Locations
Vancouver
The Vancouver campus is located at Point Grey, a twenty-minute drive from downtown Vancouver. It is near several beaches and has views of the North Shore mountains. The 7.
 (UBC UBC Uniform Building Code
UBC University of British Columbia
UBC Union of the Baltic Cities
UBC United Brotherhood of Carpenters
UBC Universal Battery Charger
UBC Union of Baltic Cities
UBC Universal Bibliographic Control
UBC Used Beverage Cans
) to which MIVT has exclusive commercial rights under a strategic alliance with the university. The latest count includes several key patent applications filed simultaneously in various countries around the world, further protecting commercial exclusivity of MIVT's inventions in the global marketplace. The patents from UBC involve MIVT's initial strategic thrust to commercialize a family of next-generation biocompatible coatings for stents and other medical devices based on a highly biocompatible material called Hydroxyapatite hydroxyapatite /hy·droxy·ap·a·tite/ (-ap´ah-tit) an inorganic calcium-containing constituent of bone matrix and teeth, imparting rigidity to these structures.  (HAp), which has been shown to be suitable for a broad array of applications as a coating for coronary stents and next-generation drug-elution/drug-delivery systems.

"The vigorous expansion and the aggressive protection of intellectual property portfolio is a central element of MIVT's high-growth business strategy. Continued growth of our family of patents, licenses and patent applications reflects methodical pursuit of important milestones of our corporate progress," said Alan Lindsay, Chairman and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of MIVT. "Our HAp-based coatings and composite drug delivery technologies have a number of potential broad applications in cardiovascular and non-vascular drug/device combination products. Our goal is to continue to develop innovative solutions needed in our target markets and to diversify our portfolio of solutions to capitalize on applications that can access the $100 billion market of combination implantable drug delivery systems."

Mr. Lindsay added, "The market for drug-eluting stents is one of the fastest growing segments within the medical device arena, with annual growth approaching 25%, and there is a critical need for next-generation technologies and solutions to enhance the performance and safety of devices, while providing competitive advantages to medical device manufacturers."

In addition to its advanced research and development programs, the Company is also expanding its intellectual property portfolio through acquisitions. Earlier this year, MIVT grew its IP portfolio through acquisition of SagaX, a company developing a range of proprietary solutions to prevent naturally occurring cardio-embolic strokes and strokes and other common and serious complications that can result from cardiac procedures. These technologies include an innovative proprietary Aortic Embolic embolic /em·bol·ic/ (em-bol´ik) pertaining to an embolus or to embolism.

em·bol·ic
adj.
1. Relating to, or caused by an embolus or embolism.

2. Relating to emboly.
 Protection Device (AEPD),designed to be implanted in the aorta during cardiology surgery and procedures, to filter and/or deflect embolic particles that can cause seriously debilitating de·bil·i·tat·ing
adj.
Causing a loss of strength or energy.


Debilitating
Weakening, or reducing the strength of.

Mentioned in: Stress Reduction
 or fatal strokes if left in blood circulation. The unique AEPD technology being developed at MIVT's SagaX subsidiary is one of the latest innovations in the field of filter-based embolic protection devices. It is the only filter being developed for use in the aorta. SagaX is also developing other proprietary embolic protection technologies.

The global market for carotid carotid /ca·rot·id/ (kah-rot´id) pertaining to the carotid artery, the principal artery of the neck.

ca·rot·id
n.
 stents and embolic filters, which are frequently implanted in combination with each other for stroke prevention purposes, is growing around the world. Currently, the global market for these devices is estimated at $130 million, but analysts forecast that such devices will grow into a $500 million to $1 billion segment of the stent market, according to published reports.

About MIV Therapeutics, Inc.

MIV Therapeutics, Inc. is developing a next-generation line of advanced biocompatible coatings for passive and drug-eluting application on cardiovascular stents and for application on other implantable medical devices. The Company's unique ultra-thin coatings, as well as its drug-eluting coatings, are based on a ceramic material called hydroxyapatite (HAp), a bioactive porous material that makes up the bone mineral and matrix of teeth and is widely used as a bone substitute material and for coating implantable fixation devices in orthopedic, dental and other applications. During in-vivo animal trials HAp has demonstrated exceptional biocompatibility biocompatibility

the quality of not having toxic or injurious effects on biological systems.

biocompatibility 1. The extent to which a foreign, usually implanted, material elicits an immune or other response in a recipient 2.
 and excellent safety pursued by the science in the field of advanced implantable drug delivery systems. The Company's ultra-thin coating formulation is designed primarily to protect surrounding tissue from the chemical interaction with metal stents. The Company's novel drug eluting technologies are designed to provide an advanced alternative solution to polymer-based drug eluting coatings currently in the stent market. The Company's composite drug eluting coating technologies are designed to suit a broad range of implantable medical devices which may benefit from a highly customizable drug release profile. MIVT reached a Collaborative Research Agreement (CRA See Community Reinvestment Act. ) with the University of British Columbia and supported a research and development grant from the Natural Sciences and Engineering Research Council The Natural Sciences and Engineering Research Council (NSERC) is a Canadian government division that provides grants for research in the natural sciences and in engineering. In 2004-2005, it will invest CAD $850 million in university-based research and training.  of Canada (NSERC NSERC Natural Sciences and Engineering Research Council (Canada)
NSERC Naval Systems Engineering Resource Center
) in 2002 for the development of Hydroxyapatite as a drug-eluting coating. In December 2004 MIVT received a Government grant for the research program titled "Development of Novel Drug Eluting Composite Coatings for Cardiovascular Stents". For more information, please visit: http://www.trilogy-capital.com/tcp/mivt/website.html. To read or download MIV Therapeutics' Investor Fact Sheet, visit http://www.trilogy-capital.com/tcp/mivt/factsheet.html. To obtain daily and historical Company stock quote data, and recent Company news releases, visit http://www.trilogy-capital.com/tcp/html/mivt.htm. MIVT is also traded on the Frankfurt Stock Exchange Frankfurt Stock Exchange

The largest of Germany's eight securities exchanges, operated by Deutsche Borse AS.
 under the ticker symbol MIV.

Forward-Looking Statements

Except for the historical information contained herein, the matters discussed in this press release are forward-looking statements. Such statements are indicated by words or phrases such as "believe," "will," "breakthrough," "significant," "indicated," "feel," "revolutionary," "should," "ideal," "extremely" and "excited." These statements are made under "Safe Harbor" provisions of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. Actual results may differ materially from those described in forward-looking statements and are subject to risks and uncertainties. See the Company's filings with the Securities and Exchange Commission including, without limitation, the Company's recent Form 10-K and Form 10-Qs, which identify specific factors that may cause actual results or events to differ materially from those described in the forward-looking statements.
COPYRIGHT 2005 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2005, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1CANA
Date:Sep 26, 2005
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