MDEChem, Inc. Issues Corporate Update.

HOUSTON -- MDEChem, Inc. (PINK SHEETS:MDKM) is pleased to present to its shareholders and all interested parties a corporate update of developments pertaining to publicity, marketing and sales for the EnviroFuels LP Diesel Fuel Catalyzer (DFC) and the introduction and distribution of MaxHeal products used in animal and human health applications.

At the end of September, EnviroFuels LP reports they were selling their DFC to more than 20 railroads and have commenced marketing the DFC to other industry sectors. EnviroFuels LP also reported that sales for the 3rd Quarter of 2005 were 116% higher than the same period last year. Why? The formula is simple. For every dollar they spend on the Diesel Fuel Catalyzer, the railroads save $2.50-$5.00 in diesel fuel expense (based on the ETV Report and current market prices for diesel fuel). Most of 3rd quarter sales were attributed to the railroad industry, but remember that the DFC is a consumable product with many industries. Newsworthy publicity of the terrific ETV test results will come with sales and the Company is confident that all diesel fuel users will be satisfied consumers of the DFC, no matter what their application. For more information, please visit www.envirofuelslp.com.

Years of testing went into the development of the Diesel Fuel Catalyzer for use in all diesel fuel applications including but not limited to railroad locomotives, cruise ships, commercial ships, power generation plants and off road applications in mining and construction. This product can save hundreds of millions in fuel costs, while at the same time reducing harmful emissions from the air. The U.S. EPA ETV (Environmental Testing Verification) Unit conducted the ETV testing of the EnviroFuels Diesel Fuel Catalyzer (DFC) on a EMD 16-645E3 locomotive. The test results published by the Greenhouse Gas Technology Center at the Southern Research Institute observed that there was a statistically significant reduction in fuel consumption of 5% to 10%. This translates into some very big numbers when considering the size and scope of the diesel fuel market. Additionally, there were statistically significant reductions in CO2, NOx, CO, and THC emissions. EnviroFuels DFC is the first stand alone, patented and EPA verified fuel technology that provides both benefits.

MDEChem is also confident with the progress of its MaxHeal line of Animal & Human applications and has commenced plans to market these products in North America in 2006. A number of MaxHeal products are currently being sold in Central America with fine results and the number of applications available with the MaxHeal technology is quite amazing. For more information on MaxHeal, go to www.mdechem.com.

The Company is very pleased with its progress and with the positive developments that have been accomplished this past calendar year. Our stock is up some 500%+ since the 1st of the year, and we look for an excellent year in 2006 with much to report. We are very grateful to our shareholders for their support over the years and as always we welcome any comments, questions, and inquiries.

Safe Harbor Notice

This document contains "forward-looking statements" as provided in the Securities Act of 1933 and the Securities Exchange Act of 1934. MDEChem, Inc. believes that the expectations reflected in the above statements are reasonable, but no assurances can be given that they will prove correct. Statements made herein are not a guarantee of future corporate or stock performance. This information should not be construed as investment advice. All information is believed to be reliable, but cannot be guaranteed. The above information is not a solicitation to buy or sell securities. Always consult with a registered investment professional prior to investing.