Low cholesterol may cut risk for high-grade prostate cancer.Byline: ANI Washington, Nov 4 (ANI): Men with low cholesterol levels are less likely to suffer from aggressive form of prostate cancer prostate cancer, cancer originating in the prostate gland. Prostate cancer is the leading malignancy in men in the United States and is second only to lung cancer as a cause of cancer death in men. , say researchers. The study led by Johns Hopkins Noun 1. Johns Hopkins - United States financier and philanthropist who left money to found the university and hospital that bear his name in Baltimore (1795-1873) Hopkins 2. researchers showed that having lower levels of heart-clogging fat might cut a man's risk of high grade prostate cancer by nearly 60 percent. "For many reasons, we know that it's good to have a cholesterol level within the normal range," said Elizabeth Platz The Rev Elizabeth Alvina Platz was the first woman in North America ordained by a Lutheran church body. She was ordained in November 1970 into the Lutheran Church in America (LCA). , Sc.D., M.P.H., associate professor at the Johns Hopkins Bloomberg School of Public Health The Johns Hopkins Bloomberg School of Public Health is part of Johns Hopkins University in Baltimore, Maryland, U.S. It was the first institution of its kind in the world. Founded in 1916 by William H. Welch and John D. and co-director of the cancer prevention and control program at the Johns Hopkins Kimmel Cancer Centre. "Now, we have more evidence that among the benefits of low cholesterol may be a lower risk for potentially deadly prostate cancers," she added. During the study, researchers analyzed data from 5,586 men aged 55 and older enrolled in the Prostate Cancer Prevention Trial from 1993 to 1996. Some 1,251 men were diagnosed with prostate cancer during the study period. They found that men with cholesterol levels lower than 200 mg/dL had a 59 percent lower risk of developing high-grade prostate cancers, which tend to grow and spread rapidly. Cholesterol levels had no significant effect on the entire spectrum of prostate cancer incidence, only those that were high-grade, said Platz. However, Platz cautions that, while the group took into account factors that could bias the results, such as smoking history, weight, family history of prostate cancer, and dietary cholesterol, other things could have affected their results. One example is whether men in the study were taking cholesterol-lowering drugs cholesterol-lowering drug Therapeutics Any of a family of agents that ↓ serum cholesterol; the most cost-effective agents for lowering LDL-C are nicotinic acid and lovastatin; the most efficient for ↑ HDL-C are nicotinic acid and gemfibrozil at the time of the blood collections, a data point the researchers expect to analyze soon. "Cholesterol may affect cancer cells cells once believed to be peculiar to cancers, but now know to be epithelial cells differing in no respect from those found elsewhere in the body, and distinguished only by peculiarity of location and grouping. See also: Cancer at a level where it influences key signaling pathways controlling cell survival. Cancer cells use these survival pathways to evade the normal cycle of cell life and death," said Platz. The study appears in the journal Cancer Epidemiology, Biomarkers and Prevention. (ANI) Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency. (ANI) - All Rights Reserved. Provided by Syndigate.info an Albawaba.com company |
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