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Long search reveals cell receptor for plant growth.


More than 70 years after biologists identified the powerful plant hormone plant hormone
n.
Any of various hormones produced by plants that control or regulate germination, growth, metabolism, or other physiological activities. Also called phytohormone.
 auxin, they have finally found "Finally Found" was the debut single from the Honeyz. This was their most successful single in the UK and worldwide, securing a number 4 position in the UK singles chart and achieved platinum status in Australia [1] Tracklisting

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 how plant cells detect it.

Auxin plays a role in just about every aspect of plant growth, from roots to shoots. Gardeners use auxin-containing products to coax cuttings to take root and overdoses of auxin to kill weeds.

In the long search to understand how auxin works, biologists have had trouble figuring out step one: how a cell detects the hormone in the first place. In the May 26 Nature, two research groups independently report finding an auxin receptor in plant cells. It turns out to be a previously recognized molecule called transport inhibitor response 1 protein (TIR TIR International Road Transport [French Transports Internationaux Routiers] 1).

One team, led by Mark Estelle Mark Estelle (born July 29, 1981) is a defensive back for the Montreal Alouettes of the Canadian Football League. He has formerly played for the Houston Texans of the National Football League and the Cologne Centurions of NFL Europe.  of Indiana University Indiana University, main campus at Bloomington; state supported; coeducational; chartered 1820 as a seminary, opened 1824. It became a college in 1828 and a university in 1838. The medical center (run jointly with Purdue Univ.  in Bloomington, identified the receptor by using engineered insect cells to produce TIR1. The researchers then tested whether the protein would combine with auxin in a simplified environment devoid of hundreds of other plant chemicals. By adding specific compounds known to interact with auxin, the team confirmed that TIR1 binds directly to auxin.

Similar results with TIR1 made by frog cells came from the other team, led by Stefan Kepinski of the Umea Plant Science Center in Sweden and Ottoline Leyser of the University of York This article is about the British university. For the Canadian university, see York University.
The University of York is a campus university in York, England.
 in England.

The two studies suggest that auxin and its receptor spur growth by releasing cells' parking brakes. When the hormone docks into a TIR1 protein, it prompts the cell to destroy certain inhibitors of cell-growth genes.--S.M.
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Title Annotation:BOTANY
Publication:Science News
Article Type:Brief Article
Geographic Code:1USA
Date:Jul 2, 2005
Words:248
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