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Locus Pharmaceuticals, Inc. to Present at Windhover Information's 'The Start-Up Forum 2005'.


BOSTON -- Locus Pharmaceuticals, Inc., a computationally-based pharmaceutical company focused on small molecule therapeutics, has announced that it will be presenting on May 19 at 12:20 p.m. at Windhover wind·hov·er  
n. Chiefly British
A kestrel.
 Information's "The Start-Up Forum 2005", taking place May 18-20, 2005 at the Cambridge Marriott in Boston, MA.

Locus is an IND-directed pharmaceutical company that is a world leader in computational drug design. The Company is privately-held and is based in Blue Bell, Pennsylvania Blue Bell is a census-designated place (CDP) in Whitpain Township in Montgomery County, Pennsylvania, in the United States. As of the 2000 census, its population was 6,395. , near Philadelphia.

Locus is focused on applying its technology in cancer and inflammation for the development of oral therapies. The Company currently has three IND tracking programs in these areas. In addition, Locus is exploring the possible application of certain programs in AIDS/HIV, macular degeneration macular degeneration, eye disorder causing loss of central vision. The affected area, the macula, lies at the back of the retina and is the part that produces the sharpest vision.  and obesity. All of our development activities emanate from the computational technology.

Locus uses unique computational approaches to design and optimize novel drug candidates. These capabilities are combined with in-house chemistry, biology and crystallography to create a fully integrated drug discovery platform. The technology addresses the two major unmet needs in computational design: (1) to accurately predict the binding potency of a ligand-protein interaction and (2) to accurately simulate real-life movements of this moiety moiety: see clan. . We believe that over time our technology offers the potential to lower the cost of drug discovery/development and greatly increase the speed of getting compounds into humans.

Locus has a pipeline of drugs in development for the treatment of certain cancers, inflammatory disease Noun 1. inflammatory disease - a disease characterized by inflammation
disease - an impairment of health or a condition of abnormal functioning

NEC, necrotizing enterocolitis - an acute inflammatory disease occurring in the intestines of premature infants;
 (e.g., arthritis, cardiovascular) and AIDS/HIV. Locus' most advanced programs are in oncology; each of which involves a distinct mechanism of action and is designed for oral dosage. An anti-mitotic is Locus' first clinical candidate, for which an IND is expected to be filed around the end of 2005. A second cancer compound could follow into the clinic in the second half of 2006. In our inflammation program it is also possible that we will have a compound in the clinic during 2006.

Our principal shareholders include Prism Venture Partners, Sarnoff Corporation Sarnoff Corporation, with headquarters in Princeton, New Jersey, is the former RCA Laboratories. The headquarters is the site of the development of color television, CMOS technology, electron microscopy, and many other important technologies since the cornerstone was laid just , Cooper Hill, Delphi Ventures, Dresdner Kleinwort Dresdner Kleinwort (DKIB) is the investment bank of Dresdner Bank AG, part of Allianz since July 2001. Headquartered in London and Frankfurt and with an international network including offices in the financial centres of New York and Tokyo, Dresdner Kleinwort provides a wide range  Capital and Johnson & Johnson Development Corporation.
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Publication:Business Wire
Geographic Code:1USA
Date:May 11, 2005
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