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Lipomics Technologies Launches Insight Metabolic Pathway Maps and Signature Flux Equations.


Business Editors/Health/Medical Writers

BIOWIRE2K

WEST SACRAMENTO, Calif.--(BUSINESS WIRE)--Sept. 8, 2003

Lipomics Technologies Inc., a privately owned company that specializes in lipid metabolite metabolite, organic compound that is a starting material in, an intermediate in, or an end product of metabolism. Starting materials are substances, usually small and of simple structure, absorbed by the organism as food.  research and analytical services, today announced

two new products for metabolic research, Lipomics Insight(TM) and Signature(TM).

Lipomics Insight(TM) metabolic pathway maps assemble the results of TrueMass(R) lipid metabolite measurements, with Signature(TM) flux equations, to generate an informative graphical representation of a lipid metabolism Lipid metabolism

The assimilation of dietary lipids and the synthesis and degradation of lipids; this article is restricted to mammals.

The principal dietary fat is triglyceride.
. An Insight map can be used, for example, to evaluate the metabolic effects of drug compounds or to establish the mechanism of unusual drug response. Insight pathway maps launched today include those representing lipid metabolism in plasma or serum, liver, adipose adipose /ad·i·pose/ (ad´i-pos)
1. fatty.

2. the fat present in the cells of adipose tissue.


ad·i·pose
adj.
Of, relating to, or composed of animal fat; fatty.
, muscle and heart tissue as well as maps for specific metabolic processes Noun 1. metabolic process - the organic processes (in a cell or organism) that are necessary for life
metabolism

organism, being - a living thing that has (or can develop) the ability to act or function independently
 including lipogenesis lipogenesis /lipo·gen·e·sis/ (-jen´e-sis) the formation of fat; the transformation of nonfat food materials into body fat.lipogenet´ic

lip·o·gen·e·sis
n.
1.
 and essential fatty acid
    Essential fatty acids, or EFAs, are fatty acids that cannot be constructed within an organism from other components (generally all references are to humans) by any known chemical pathways; and therefore must be obtained from the diet.
     metabolism.

    Signature(TM) equations use TrueMass(R) data to estimate the steady-state flux of lipid metabolites Metabolites
    Substances produced by metabolism or by a metabolic process.

    Mentioned in: Interactions
     through key lipid metabolism pathways. Signature equations have been developed and empirically tested using the company's extensive database experimental subjects and its institutional knowledge of lipid metabolism.

    TrueMass(R) analysis, Lipomics core product, is a proprietary system for quantifying hundreds of lipid metabolites in biological sample.

    Insight(TM) and Signature(TM) products are available exclusively to Lipomics research alliance partners.

    About Lipomics Technologies, Inc.

    Lipomics develops tools for drug discovery and patient monitoring based on its proprietary technologies for lipid metabolite analysis and data interpretation. The company generates knowledge of lipid metabolism by combining quantitative measurements of lipid metabolites in plasma or tissue samples with proprietary algorithms for mapping the resulting profiles to biochemical pathways. In partnership with pharmaceutical companies, Lipomics uses its technology to speed drug discovery processes, improve clinical trial stratification, reduce late-stage drug attrition, and to develop early tests for monitoring drug response. The Company's products and technologies include TrueMass(R) lipid analysis platform, Signature(TM) algorithms for linking lipomic profiles to biochemical pathways, Surveyor(TM) data visualization See information visualization.  software, and Insight(TM) software for assembling metabolite concentration and enzyme flux data into a quantitative pathway map.

    Recently updated information, news postings and resources for understanding lipids and their role in health and disease can be found online at www.lipomics.com.

    TrueMass(R) is a registered US trademark of Lipomics Technologies, Inc.

    Lipomics Insight(TM) and Signature(TM) are trademarks of Lipomics Technologies Inc.
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    No portion of this article can be reproduced without the express written permission from the copyright holder.
    Copyright 2003, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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    Publication:Business Wire
    Geographic Code:1USA
    Date:Sep 8, 2003
    Words:386
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