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LIFECELL'S ALLODERM(R) PROCESSED TISSUE GRAFT FEATURED IN NEW TECHNIQUE FOR WOUND TREATMENT; STUDY SHOWS ALLODERM DERMAL TISSUE GRAFT COMBINED WITH CULTURED SKIN PRODUCT MAY EFFECTIVELY ELIMINATE NEED FOR SELF-DONATED SKIN GRAFTS.


THE WOODLANDS, Texas--(BUSINESS WIRE)--Aug. 29, 1995--LifeCell Corporation (Nasdaq:LIFC) today announced the publication of a new technique in wound management that features the use of AlloDerm processed tissue in a composite skin graft skin graft Autologous, donated, or surrogate skin removed from one site to cover surfaces on another region with 3rd-degree burns or traumatic tissue loss. See Split-thickness graft. Cf Artificial skin, 'Spray-on' skin.  that could effectively eliminate the need for self-donated skin grafts to treat burn wounds. The new technique was reported in the July/August 1995 edition of Wounds, a compendium of clinical research and practice, and presented at the Seventh International Symposium on Wound Healing wound healing Physiology The repair of a wound Steps Inflammation, repair and closure, remodeling, final healing; repair of incisions may be either simple–'clean' wounds with little loss of tissue heal by 'primary intention', or 'dirty' wounds heal by  and Wound Management.

The Wounds article reviewed three case studies in which AlloDerm processed dermal dermal /der·mal/ (der´mal) pertaining to the dermis or to the skin.

der·mal or der·mic
adj.
Of or relating to the skin or dermis.
 tissue grafts were combined with a simultaneous application of cultured epithelial autografts (CEA CEA carcinoembryonic antigen.

CEA
abbr.
carcinoembryonic antigen


CEA (Carcinoembryonic antigen) 
) to produce a composite skin for treatment of deep-partial and full-thickness wounds. The studies highlighted that the new technique "eliminates the need to harvest the patient's own skin (with the exception of the biopsy for CEA)." In addition, the study noted that use of the AlloDerm tissue graft promoted faster wound healing and increased skin durability than with CEA alone.

"The positive data from these case studies highlights the progress being made in the development of an off-the-shelf skin graft product that may virtually eliminate patient donor grafts," stated Paul M. Frison, President and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of LifeCell. "LifeCell is currently developing techniques for culturing human kerantinocytes, the primary epidermal cell type present in human skin, onto the surface of AlloDerm processed tissue. If proven clinically effective, LifeCell's composite skin graft would be a major advancement in the treatment of burns and other wounds requiring skin grafts."

The case studies were conducted by a team of clinicians from the Nathan Speare Regional Burn Treatment Center, Crozer-Chester Medical Center, Upland, Pennsylvania, including: Jonathan D. Kraut kraut  
n.
1. Sauerkraut.

2. often Kraut Offensive Slang Used as a disparaging term for a German.



[German; see sauerkraut.]

Noun 1.
, BS; Aric J. Eckhardt, MD; Mary Lou Patton, MD, FACS FACS Fellow of the American College of Surgeons.

FACS
abbr.
Fellow of the American College of Surgeons



FACS

fluorescence-activated cell sorter.
; Kristina Antoniades, MD; Linwood R. Haith, Jr., MD, FACS and Barbara S. Shotwell, MD.

LifeCell Corporation is an industry leader in the development and commercialization of universal tissue grafts and blood preservation products. AlloDerm(R) universal dermal tissue graft is the Company's first commercial product and is used in the treatment of third-degree burns, in periodontal surgery periodontal surgery, (per´ēōdon´tl),
n
 and in plastic and reconstructive surgery. In addition to the Company's universally transplantable tissue grafts, LifeCell's product development programs include ThromboSol(R), a formulation for extending the shelf-life of transfusable platelets.

CONTACT: LifeCell Corporation, The Woodlands

Jane Lea Hicks, 713/367-5368
COPYRIGHT 1995 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1995, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Aug 29, 1995
Words:388
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