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Killing bacteria effectively and safely.


Killing bacteria effectively and safely

Dormant bacteria can be difficult to get rid of with conventional antibiotics, which work on dividing bacteria but leave resting ones alone. Nondormant bacteria that are killed by antibiotics can also present a problem. Two studies presented by New York City New York City: see New York, city.
New York City

City (pop., 2000: 8,008,278), southeastern New York, at the mouth of the Hudson River. The largest city in the U.S.
 researchers at the recent American Society for Microbiology The American Society for Microbiology (ASM) is a scientific organization, based in the United States although with over 43,000 members throughout the world. It is the largest single life science professional organization and its members include those whose interests encompass basic  meeting suggest solutions to an example of each problem.

Elaine Tuomanen, Alexander Tomasz and their colleagues at Rockefeller University Rockefeller University, philanthropic organization in New York City, founded 1901 as the Rockefeller Institute for Medical Research by John D. Rockefeller for furthering medical science and its allied subjects and to make knowledge of these subjects available to the  tested a recently developed class of antibiotics called penems against dormant bacteria. The penems, they found in in vitro in vitro /in vi·tro/ (in ve´tro) [L.] within a glass; observable in a test tube; in an artificial environment.

in vi·tro
adj.
In an artificial environment outside a living organism.
 studies, can somehow kill dormant bacteria.

The group also tackled the question of why successful antibiotic therapy against nondormant bacteria that cause meningitis doesn't ensure survival. Hypothesizing that components of the killed bacteria cause potentially fatal inflammation of already-inflamed nerve tissue nerve tissue
n.
A highly differentiated tissue composed of nerve cells, nerve fibers, dendrites, and neuroglia.
, they gave anti-inflammatory agents along with antibiotics to rabbits with induced meningitis. The agents limited inflammation and improved the rabbits' survival rate.
COPYRIGHT 1986 Science Service, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1986, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Science News
Date:Nov 1, 1986
Words:155
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