Kidney, liver transplant study for people with HIV.

Atlanta, Baltimore, Boston, Charlottesville, Chicago (2 Centers), Cincinnati, Cleveland, Los Angeles, Miami, New Orleans, New York (2 Centers), Philadelphia (2 Centers), Pittsburgh, San Francisco, Washington DC (2 Centers)

This study of kidney and liver transplantation for persons with HIV, by 19 transplant centers with funding from the U.S. National Institutes of Health is currently running and is open for new people Even for patients who do not need a transplant immediately but may need one in the future, it can be important to get into the system now to avoid delays if and when a transplant is necessary. Persons with hepatitis C or hepatitis B are not disqualified and will be considered for this study.

Volunteers must:

* Meet the criteria for transplantation;

* Have a T-cell count greater than 100 (liver transplant) or greater than 200 (kidney transplant);

* Meet HIV viral load criteria depending on which organ is needed;

* Patients with certain opportunistic infections in the past will be considered, and need to have a T-cell count above 200;

* Pediatric patients are being enrolled in several centers in cities listed above.

For More Information

Specific site and study information can be found at http://spitfire.emmes.com/study/htr/About_Us/about_us.html (might require Internet Explorer browser), or http://www.clinicaltrials.gov/

Related published literature can be found at http://spitfire.emmes.com/study/htr/Useful_Links/useful_links.html

A poster at the recent Retroviruses conference reported the pilot study results so far:

Michelle Roland, M.D., Don Stablein, Laurie Carlson, and others. 1- to 3-year outcomes in HIV-infected liver and kidney transplant recipients. 12th Conference on Retroviruses and Opportunistic Infections, Boston, February 22-25, 2005 [abstract 953]. This poster may be available at http://www.retroconference.org.