Kao Elucidates How Skin Flecks Appear.Tokyo, Japan, Jan 25, 2006 - (JCN JCN Japan Corporate News JCN Journal of Cognitive Neuroscience JCN Journal of Cardiovascular Nursing JCN Journal of Christian Nursing JCN Job Control Number JCN Journal of Child Neurology JCN joint communications network (US DoD) ) - Kao, a leading Japanese cosmetics and toiletries manufacturer, announced on January 24 that its Biological Science Research Laboratories have elucidated the mechanism of skin flecks by quantitatively analyzing endothelin and stem cell factor stem cell factor n. A cytokine that promotes the differentiation and growth of hematopoietic stem cells into other types of cells. (SCF SCF Service Canadien des Forêts (Canadian Forest Service) SCF Stem Cell Factor SCF Scientific Committee on Food (European Commission) SCF Service Canadien de la Faune ), a substance involved in melanocyte melanocyte /mel·a·no·cyte/ (mel´ah-no-sit) (me-lan´o-sit) any of the dendritic clear cells of the epidermis that synthesize tyrosinase and, within their melanosomes, the pigment melanin; the melanosomes are development. According to the research, since the overproduction o·ver·pro·duce tr.v. o·ver·pro·duced, o·ver·pro·duc·ing, o·ver·pro·duc·es To produce in excess of need or demand. o of melanine is induced by endothelin and SCF even if the skin is no longer exposed to ultraviolet rays, skin flecks tend to be persistent. Further, SCF exists in cells of the pigmented parts so that the development of melanocyte is locally enhanced, making the skin flecks sharply visible. In addition, the research group has developed AM Chromone, a chromone derivative that inhibits the proliferation of melanocyte. In the recent clinical studies, the group has confirmed a high inhibitory effect of AM Chromone. Kao plans to apply these findings to the development of new whitening cosmetics. Details of the latest achievements were presented at the 14th Japan-Korea Joint Meeting of Dermatology in November and will also be presented at the 126th Annual Meeting of the Pharmaceutical Society of Japan in March. Copyright [c] 2006 Japan Corporate News Network. All rights reserved. |
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