Invitrogen Corporation Awarded Contract Extension for Biothreat Detection by U.S. Department of Defense.CARLSBAD, Calif. -- Invitrogen Corporation (Nasdaq:IVGN), a leading life science company providing innovative technologies to support disease research and drug discovery, today announced that its subsidiary, Invitrogen Federal Systems, was awarded a $1,243,000 extension to an existing contract with the U.S. Department of Defense. The contract will support research using Invitrogen's proprietary ProtoArray(TM) protein microarray A protein microarray is a piece of glass on which different molecules of protein have been affixed at separate locations in an ordered manner thus forming a microscopic array. technology to detect and analyze biothreat agents such as hemorrhagic fever hemorrhagic fever (hĕm'ərăj`ĭk), any of a group of viral diseases characterized by sudden onset, muscle and joint pain, fever, bleeding, and shock from loss of blood. viruses, poxviruses and Bacillus anthracis Bacillus anthracis Infectious disease A gram-positive organism which causes often fatal infections when its endospores–resistant to heat, drying, UV light, gamma radiation, and many disinfectants–enter the body and cause septicemia Military medicine (anthrax anthrax (ăn`thrăks), acute infectious disease of animals that can be secondarily transmitted to humans. It is caused by a bacterium (Bacillus anthracis ). This research will build upon work conducted under the original Technical Assistance Agreement for $970,000 awarded in January 2006, which focused on the detection and analysis of smallpox and Yersinia pestis Yersinia pes·tis n. A bacterium that causes plague and is transmitted from rats to humans by the rat flea Xenopsylla cheopis. Also called Pasteurella pestis. (plague). "We look forward to working closely with the Army to produce and validate ProtoArray protein microarrays that will improve the military's ability to detect dangerous bacteria and viruses," said Gregory T. Lucier, Chairman and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. of Invitrogen Corporation. "Invitrogen has developed a broad suite of biodefense technologies that can detect various biothreat agents in air, food and water." ProtoArray is a functional, high density protein microarray that can analyze entire pathogen and yeast proteomes or up to 5,000 human proteins in a single experiment, while other currently available protein microarrays are limited to 500 proteins. Additionally, ProtoArray can be used to simultaneously analyze proteins, antibodies or small molecules, simplifying work that traditionally took months to achieve into a single day. In addition to biodefense applications, Invitrogen uses ProtoArray to identify protein biomarkers associated with cancer and autoimmune diseases Autoimmune diseases A group of diseases, like rheumatoid arthritis and systemic lupus erythematosus, in which immune cells turn on the body, attacking various tissues and organs. Mentioned in: Complement Deficiencies, Premature Menopause as well as in drug discovery research and functional genomics Noun 1. functional genomics - the branch of genomics that determines the biological function of the genes and their products genomics - the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences) . "In the near term, the type of research that Invitrogen is conducting will support the identification of protein biomarkers associated with biothreat agents, leading to the development of better, faster detection tools, diagnostics and vaccines," explained Paul Kinnon, General Manager for Environmental Diagnostics at Invitrogen, which includes biodefense research as well as food and water safety testing. "In the longer term, these findings will be the first step in developing personalized medicine Invitrogen's research on this project will be conducted under the direction of James Meegan, Ph.D., Senior Director of Research & Development at Invitrogen, and is designed to support the U.S. Army Medical Research and Materiel ma·te·ri·el or ma·té·ri·el n. The equipment, apparatus, and supplies of a military force or other organization. See Synonyms at equipment. Command's (USAMRMC USAMRMC United States Army Medical Research and Materiel Command ) mission to provide solutions to medical problems of importance to the American war fighter at home and abroad. Robert Ulrich, Ph.D., is responsible for scientific and technical conduct of this project at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID USAMRIID United States Army Medical Research Institute of Infectious Diseases (US DoD) ). In addition to the ProtoArray, Invitrogen has developed other technologies for the detection of pathological agents, including the PathAlert(TM) System, which was used by Instituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, part of the Italian Ministry of Health, to detect Yersinia pestis during the 2006 Winter Olympic games. The PathAlert(TM) System has also been used to ensure public safety at other international public events including the 2006 Commonwealth Games and has been part of a Technical Readiness Assessment at the U.S. Army's Dugway Proving Grounds, where the system was found to be a sensitive and specific molecular based approach for testing a number of biothreat agents such as anthrax and plague. About USAMRIID The U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), located at Fort Detrick, Maryland, is the lead medical research laboratory for the U.S. Biological Defense Research Program, and plays a key role in national defense and in infectious disease Infectious disease A pathological condition spread among biological species. Infectious diseases, although varied in their effects, are always associated with viruses, bacteria, fungi, protozoa, multicellular parasites and aberrant proteins known as prions. research. The Institute's mission is to conduct basic and applied research on biological threats resulting in medical solutions (such as vaccines, drugs and diagnostics) to protect the warfighter. USAMRIID is a subordinate laboratory of the U.S. Army Medical Research and Materiel Command. This project has been funded by the U.S. Department of the Army under Technical Assistance Agreement W81XWH-05-2-0077. The U.S. Army Medical Research Acquisition Activity, 820 Chandler Street, Fort Detrick, MD 21702-5014 is the awarding and administering acquisition office. Information contained in this press release does not necessarily reflect the position or the policy of the Government, and no official endorsement is inferred. About Invitrogen Corporation Invitrogen Corporation (Nasdaq:IVGN) provides products and services that support academic and government research institutions and pharmaceutical and biotech companies worldwide in their efforts to improve the human condition. The company provides essential life science technologies for disease research, drug discovery, and commercial bioproduction. Invitrogen's own research and development efforts are focused on breakthrough innovation in all major areas of biological discovery including functional genomics, proteomics and cell biology -- placing Invitrogen's products in nearly every major laboratory in the world. Founded in 1987, Invitrogen is headquartered in Carlsbad, California, and conducts business in more than 70 countries around the world. The company globally employs approximately 4,800 professionals and had revenues of more than $1.2 billion in 2005. For more information, visit www.invitrogen.com. Safe Harbor Safe Harbor 1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated. 2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive. Statement Certain statements contained in this press release are considered "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995, and it is Invitrogen's intent that such statements be protected by the safe harbor created thereby. Forward-looking statements include, but are not limited to: 1) Identification of protein biomarkers using ProtoArray will lead to improved detection tools, diagnostics and vaccines; and 2) The use of ProtoArray will lead to the development of personalized medicine applications for military use. Potential risks and uncertainties include, but are not limited to, the risks: a) ProtoArray's use may have no significant impact on future diagnostics or other applications; and b) Applications utilizing ProtoArray may not develop or further personalized medicine in the military area, as well as other risks and uncertainties detailed from time to time in Invitrogen's Securities and Exchange Commission filings. |
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