Inside story.Your article "Cancer Link: Gene regulates progesterone 1. A steroid hormone steroid hormone n. secreted by the corpus luteum and by the placenta, that acts to prepare the uterus for implantation of the fertilized ovum, to maintain pregnancy, and to promote development of the mammary glands. Also called corpus luteum hormone, luteohormone, progestational hormone. See steroid. 2. effect on breast cells" (SN: 12/2/06, p. 355) made a common mistake in characterizing the mechanism of steroid-hormone receptors. These receptors are not "proteins on the cell surface" but rather, and uniquely, positioned intracellularly. Steroid hormones pass directly from the bloodstream blood·stream (bl d str m )n. to the cytoplasm cyto·plasmic (-pl zm, where they induce changes in the receptor proteins receptor proteinn. , enable movement into the nucleus, and activate specific genes. An intracellular protein or protein fraction having a high specific affinity for binding agents known to stimulate cellular activity, such as a steroid hormone or cyclic AMP. MAC BLACK, SEATTLE, WASH. |
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