Implantable medical device having biologically active polymeric casing.
U.S. patent: 6,968,234
Issued: November 22, 2005
Inventor: Kenneth B. Stokes
Key statement: An implantable medical device has a medical unit, such as a pacemaker lead, and a casing at least partially enclosing the medical unit. The casing is formed of a base polymer such as polyurethane, a polyurethane copolymer copolymer: see polymer. , a fluoropolymer A fluoropolymer is a polymer that contains atoms of fluorine. It is characterized by a high resistance to solvents, acids, and bases.
Fluoropolymers were discovered serendipitously in 1938 by Dr. Roy J. Plunkett. and a polyolefin or a silicone rubber. The casing has biologically active agents covalently bonded to the base polymer. Examples of suitable biologically active agents are microbial microbial
pertaining to or emanating from a microbe.
the breakdown of organic material, especially feedstuffs, by microbial organisms. peptide agents, detergents, non-steroidal anti-inflammatory drugs Non-steroidal anti-inflammatory drugs (NSAIDs)
Aspirin, ibuprofen, naproxen, and many others.
Mentioned in: Mastocytosis , cations, amine-containing organosilicones, diphosphohated, fatty acids and fatty acid salts.