Implantable medical device having biologically active polymeric casing.U.S. patent: 6,968,234 Issued: November 22, 2005 Inventor: Kenneth B. Stokes Assigned: Medtronic Key statement: An implantable medical device has a medical unit, such as a pacemaker lead, and a casing at least partially enclosing the medical unit. The casing is formed of a base polymer such as polyurethane, a polyurethane copolymer copolymer: see polymer. , a fluoropolymer A fluoropolymer is a polymer that contains atoms of fluorine. It is characterized by a high resistance to solvents, acids, and bases. Fluoropolymers were discovered serendipitously in 1938 by Dr. Roy J. Plunkett. and a polyolefin or a silicone rubber. The casing has biologically active agents covalently bonded to the base polymer. Examples of suitable biologically active agents are microbial microbial pertaining to or emanating from a microbe. microbial digestion the breakdown of organic material, especially feedstuffs, by microbial organisms. peptide agents, detergents, non-steroidal anti-inflammatory drugs Non-steroidal anti-inflammatory drugs (NSAIDs) Aspirin, ibuprofen, naproxen, and many others. Mentioned in: Mastocytosis , cations, amine-containing organosilicones, diphosphohated, fatty acids and fatty acid salts. |
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