Impact of oxidative stress on diabetes mellitus and inflammatory bowel diseases.9781604561524 Impact of oxidative stress on diabetes mellitus and inflammatory bowel diseases. Varvaovska, Jana et al. Nova Science Publishers 2008 108 pages $39.00 Paperback RC660 Reactive oxygen species (ROS) play an important role in pathological processes of the human organism, and in cell signaling, biosynthesis, and non-specific anti-infectious defense. This brief review of the current understanding of ROS highlights research on the role of ROS in oxidative nuclear and mitochondrial DNA damage and its restoration via DNA repair processes. An introductory chapter overviews ROS under physiological and pathological conditions, antioxidant defense, antioxidant enzymes and substances from recent literature, and non- enzymatic substances of endogenous or exogenous origin. Later chapters detail recent results related to DNA oxidative damage and repair, and oxidative stress and DNA damage and repair in diabetes mellitus and inflammatory bowel diseases. B&w images are included. Information on the editor is not given. ([c]2009 Book News, Inc., Portland, OR) |
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