ImmuCell Comments on the Nature of Data Available About Nisin.Business Editors and Health/Medical Writers PORTLAND, Maine--(BUSINESS WIRE)--Dec. 14, 2001 ImmuCell Corporation (NASDAQ NASDAQ in full National Association of Securities Dealers Automated Quotations U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on :ICCC ICCC International Council for Caring Communities ICCC International Council for Computer Communication ICCC International Computer Communications Conference ICCC International Carpathian Control Conference ICCC International Conference on Computer Communications ) today commented on the nature of data available about Nisin nisin an antibiotic substance isolated from cultures of lactic acid producing streptococci and reputed to have antibacterial activity against gram-positive bacteria. , the active ingredient in WIPE OUT(R) Skin and Environment Wipes. The Company is aware of Nisin's broad spectrum antimicrobial properties principally through its experience making and selling WIPE OUT Dairy Wipes and developing MAST OUT(TM) intramammary mastitis mastitis (măstī`tĭs), inflammation of the breast. Mastitis most commonly occurs in nursing mothers between the first and third weeks after childbirth, usually of the first child. treatment and from the publicly available scientific literature. Nisin has been used world-wide since 1953 to control bacterial spoilage spoilage decomposition; said of meat, milk, animal feeds especially ensilage. in foods. Nisin has been shown to be effective against many species of bacteria, including at least 10 species of the genus Bacillus that are important in preventing food spoilage. Bacillus cereus is a principal species of Bacillus commonly found in food spoilage and outbreaks of "food poisoning". Numerous citations in the literature demonstrate Nisin's activity against Bacillus cereus bacteria and spores. The Company has confirmed the potency of its Nisin against Bacillus cereus. Bacillus anthracis is a member of the "Bacillus cereus group" and is also known as Bacillus cereus var. anthracis. However, to date, neither WIPE OUT nor Nisin has been proven to be effective against the agent of Anthrax, Bacillus anthracis. Moreover, the Company knows of no information presently available in the scientific literature which demonstrates that Nisin is effective against Bacillus anthracis (Anthrax). Because of the body of evidence showing Nisin's activity against species of the genus Bacillus and the close relationship between Bacillus cereus and Bacillus anthracis, the Company is presently seeking collaborations with laboratories working with Bacillus anthracis in order to confirm or deny the utility of Nisin preparations in the decontamination decontamination /de·con·tam·i·na·tion/ (de?kon-tam-i-na´shun) the freeing of a person or object of some contaminating substance, e.g., war gas, radioactive material, etc. de·con·tam·i·na·tion n. of environmental (skin and surface) Anthrax. The Company's commercial rights do not cover the use of Nisin preparations as a treatment for Anthrax infections. ImmuCell Corporation is a biotechnology company dedicated to benefiting its employees and shareholders through innovative and proprietary products that improve animal health and productivity in the dairy and beef industry. In addition to operating a growing and profitable animal health business, the Company has obtained U.K. regulatory approval to sell Crypto-Scan(R), a product that is used in the detection of Cryptosporidium cryptosporidium (krĭp'tōspərĭd`ēəm), genus of protozoans having at least four species; they are waterborne parasites that cause the disease cryptosporidiosis. in drinking water. Further, the Company has demonstrated preliminary efficacy in an open label, Phase I/II efficacy study of DiffGAM, an alternative to antibiotics in the treatment and/or prevention of Clostridium clostridium Any of the rod-shaped, usually gram-positive bacteria (see gram stain) that make up the genus Clostridium. They are found in soil, water, and the intestinal tracts of humans and other animals. Some species grow only in the complete absence of oxygen. difficile-associated diarrhea in humans. Certain nutritional rights to the DiffGAM technology have been licensed to a corporate partner. ImmuCell Corporation press releases and other information about the Company are available at its corporate web site at http://www.ImmuCell.com. |
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