IOM: nevirapine study is reliable.Due to questions raised about HIVNET 012, the groundbreaking study that first showed that single-dose nevirapine nevirapine /ne·vir·a·pine/ (ne-vir´ah-pen) a nonnucleoside inhibitor of HIV-1reverse transcriptase, used in combination with other antiretroviral agents in the treatment of HIV infection. could reduce transmission of HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States. from infected in·fect tr.v. in·fect·ed, in·fect·ing, in·fects 1. To contaminate with a pathogenic microorganism or agent. 2. To communicate a pathogen or disease to. 3. To invade and produce infection in. mothers to their babies, the prestigious Institute of Medicine reviewed the study at the request of the U.S. National Institutes of Health, and presented an independent assessment. It concluded that the study was conducted ethically', that the findings that nevirapine is safe and effective for preventing maternal transmission were well supported, and that policy makers and scientists can rely on the resulting data and conclusions. [1,2] The IOM IOM See: Index and Option Market report will be published in a document of about 150 pages, including an executive summary' of about 7 pages. Meanwhile, an uncorrected proof of the executive summary and complete report are available online. [2] References [1] Press release from the Institute of Medicine, April 7, 2005, http://www.iom.edu/report.asp?id=26287 (click on "Press Release"). [2] Complete report, Review of the HIVNET 012 Perinatal perinatal /peri·na·tal/ (-na´t'l) relating to the period shortly before and after birth; from the twentieth to twenty-ninth week of gestation to one to four weeks after birth. per·i·na·tal adj. HIV Prevention Study, http://books.nap.edu/catalog/11264.html. [3] For a report from the public press briefing of November 8, see Jennifer Couzin, "IOM Panel Clears HIV Prevention Study," Science, April 15, 2005, volume 308, issue 5720, page 334. |
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