Human Genetics Department at Leiden University Medical Center (LUMC) Adopts Fluidigm BioMark(TM) Real-time PCR System.Busy Core Facility to Use New Biomark Dynamic Arrays for High-Throughput Multiplexed Analyses. SOUTH SAN FRANCISCO South San Francisco, city (1990 pop. 54,312), San Mateo co., W Calif.; inc. 1908. South San Francisco has several industrial parks; its manufactures include medical supplies and equipment, foods, paint, paper products, consumer goods, and clothing. , Calif. & LEIDEN, Netherlands -- Fluidigm Corporation and BIOKE, distributor of Fluidigm systems in the Benelux, have announced that Leiden University Medical Center The Leiden University Medical Center (Dutch: Leids Universitair Medisch Centrum) or LUMC, is the university hospital affiliated with Leiden University, of which it forms the medical faculty. (LUMC LUMC Leids Universitair Medisch Centrum LUMC Leiden University Medical Center LUMC Loyola University Medical Center LUMC Lakewood United Methodist Church LUMC Littleton United Methodist Church (Littleton, Colorado) ) has purchased the BioMark Real-time PCR PCR polymerase chain reaction. PCR abbr. polymerase chain reaction Polymerase chain reaction (PCR) System. The system was installed in the laboratory of Professor Gert-Jan B. Van Ommen, head of the Department of Human Genetics Human genetics A discipline concerned with genetically determined resemblances and differences among human beings. Technological advances in the visualization of human chromosomes have shown that abnormalities of chromosome number or structure are surprisingly and founder of the Leiden Genome Technology Center (LGTC), a principal genomics facility in The Netherlands. "The LUMC has been at the forefront of technology for genetic research, and the BioMark system helps to uphold that tradition," said Dr. Van Ommen. The BioMark system is based on dynamic arrays, a new paradigm New Paradigm In the investing world, a totally new way of doing things that has a huge effect on business. Notes: The word "paradigm" is defined as a pattern or model, and it has been used in science to refer to a theoretical framework. that is far more efficient than microwell plates for TaqMan[R] assays. BioMark dynamic arrays require one fortieth the setup steps, compared to 384-well microplates, because assays are automatically assembled on-chip by means of nanofluidic networks. In addition, dynamic arrays provide a flexible means for multiplexing any 48 genes (off-the-shelf primer-probe sets) against any 48 samples, generating 2,304 assays per run. Optional analysis software enables dynamic arrays to be used for genotyping. Professor Van Ommen's laboratory also plans to use BioMark digital arrays, which are crafted to partition a single sample/reagent mixture into 765 assays. This way, target sequences are detectable even if present in low copy number or are very similar to background sequences. The digital array is useful for cancer research and disease monitoring. About Fluidigm Fluidigm Corporation develops and distributes systems based on the unique properties of Integrated Fluidic flu·id·ic adj. 1. Of, relating to, or characteristic of a fluid. 2. Relating to or controlled by fluidics. Circuits (IFCs) to control precisely fluids on a nano-volume scale. The Company's vision is to create and to lead a new industry in which IFCs bring unparalleled efficiencies to the life science and allied fields. Based in South San Francisco, California South San Francisco is a city in San Mateo County, California, United States, located on the San Francisco Peninsula in the San Francisco Bay Area. The population was 60,552 at the 2000 census. , the company is privately held and backed by premier investors: Versant Ventures, Euclid SR Partners, InterWest Partners, Alloy Ventures, Lehman Brothers Lehman Brothers Holdings Inc. (NYSE: LEH), founded in 1850, is a diversified, global financial services firm. It is a participant in investment banking, equity and fixed income sales, research and trading, investment management, private equity, and private banking. Healthcare Fund, Bio*One Capital, Bruce Burrows, Lilly BioVentures, the Invus Group, SightLine sight·line also sight line n. A line of sight, especially one between a spectator and the spectacle in a theater or stadium. Partners, AllianceBernstein, Wasatch Advisors and its affiliate, Cross Creek Capital, and GE Equity. About BIOKE BIOKE is a key provider of products and services in life sciences. The company's aim is to accelerate the progress in R&D and diagnostics of customers in academic, hospital and other research settings as well as pharmaceutical and biotechnology companies. BIOKE provides products and services in the field of genomics, proteomics & molecular diagnostics. Through many years of experience in the life sciences sector combined with a highly trained staff, excellent technical support and market knowledge is guaranteed, resulting in true added value for the company's customers. About LUMC Leiden University Medical Center (LUMC) is strongly committed to the advancement of health care, through research and innovation. In particular, the focus is on translational research, with the overall aim to accelerate findings from the laboratory to clinical application, and to the market. LUMC has a reputation as a pioneering institute, both nationally and internationally. Fluidigm and BioMark are trademarks or registered trademarks of Fluidigm Corporation. TaqMan is a trademark of Roche Molecular Systems, Inc., and F. Hoffmann-La Roche Ltd. |
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