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How to Use Thin Layer Chromatography (TLC) In Compliance With GLP/GMP Regulations Is Described In Detail Inside 2006 Edition.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c46050) has announced the addition of Applied Thin-Layer Chromatography: Best Practice and Avoidance of Mistakes, 2nd Edition to their offering.

Thin layer chromatography Thin Layer Chromatography (TLC) is a chromatography technique used to separate chemical compounds [1]. It involves a stationary phase consisting of a thin layer of adsorbent material, usually silica gel, aluminium oxide, or cellulose immobilised onto a flat,  (TLC TLC total lung capacity; thin-layer chromatography.

TLC
abbr.
1. thin-layer chromatography

2.
) is a powerful, fast and inexpensive analytical method. It has proven its usefulness in pharmaceutical, food and environmental analysis. This new edition features a completely revised chapter on documentation, now including the use of digital cameras. Selected new sorbents and instruments are also introduced.

Why has the prior edition been successful? All steps of the analytical procedure are clearly explained, starting with the choice of a suitable TLC technique and ending with data evaluation and documentation. Special emphasis is put on the proper choice of materials for TLC. Properties and functions of various materials and the TLC equipment are described, covering e. g. precoated layers, solvents and developing chambers, and including information on suppliers. Many practical hints for trouble shooting are given. All this is illustrated with numerous coloured figures. How to use TLC in compliance with GLP/GMP regulations is described in detail, including the required documentation. Therefore the reader can very easily compile his own standard operating procedures.

Based on the authors many years of practical experience, the book provides a concise introduction to the applications of thin-layer chromatography.

About the author

After working for many years for Heumann Pharma (now part of Pfizer), where she was in particular responsible for the training and education of lab technicians, Elke Hahn-Deinstrop is now a freelance consultant for thin-layer chromatography. She is author of numerous papers and frequent lecturer.

Content Outline:

INTRODUCTION

PRECOATED LAYERS

BEFORE TLC DEVELOPMENT

SOLVENT, DEVELOPING CHAMBERS AND DEVELOPMENT

EVALUATION WITHOUT DERIVATIZATION

DERIVATIZATION

EVALUATION AFTER DERIVATIZATION

DOCUMENTATION

GMP/GLP-CONFORMING TLC WORK

LOADING EFFECTS

SPECIAL METHODS IN TLC

AMD (Advanced Micro Devices, Inc., Sunnyvale, CA, www.amd.com) A major manufacturer of semiconductor devices including x86-compatible CPUs, embedded processors, flash memories, programmable logic devices and networking chips.  -

Automated Multiple Development

OPLC See OLPC.  -

Overpressured Layer Chromatography

HPPLC HPPLC High-Pressure Planar Liquid Chromatography
HPPLC High-Performance Precipitation Liquid Chromatography
 -

High Pressure Planar Liquid Chromatography

TLC-FID/FTID -

Combination Of TLC With Flame Ionization Detector A flame ionization detector (FID) is a type of detector used in gas chromatography. Principle
The Flame Ionization Detector (FID) is one of the many methods by which to analyze materials coming off of gas chromatography column.
 Or Flame Thermoionic Ionization ionization: see ion.
ionization

Process by which electrically neutral atoms or molecules are converted to electrically charged atoms or molecules (ions) by the removal or addition of negatively charged electrons.
 Detector

RPC (Remote Procedure Call) A programming interface that allows one program to use the services of another program in a remote machine. The calling program sends a message and data to the remote program, which is executed, and results are passed back to the calling  -

Rotation Planar Chromatography

For more information visit http://www.researchandmarkets.com/reports/c46050
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Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.
vipulpatel
vipul a. patel (Member): How to Use Thin Layer Chromatography (TLC) In Compliance With GLP/GMP Regulations 10/21/2008 12:53 AM
very good article

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Publication:Business Wire
Date:Nov 28, 2006
Words:336
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