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Heinz News: New Report Shows ``Sprinkles'' Are Working to Prevent and Treat Childhood Nutrition Epidemic.


Business Editors

TORONTO--(BUSINESS WIRE)--March 26, 2003

(NYSE NYSE

See: New York Stock Exchange
:HNZ HNZ HJ Heinz Co (stock symbol) )

Nutritional Supplement Developed by

Hospital for Sick Children Scientist Treats Childhood Anemia

A new report published in the Canadian Paediatric Adj. 1. paediatric - of or relating to the medical care of children; "pediatric dentist"
pediatric
 Society's Paediatrics & Child Health journal shows that adding Supplefer Sprinkles to children's meals is already working to reduce the rate of iron-deficiency anemia iron-deficiency anemia

Most common type of anemia, which may develop in times of high iron loss and depletion of iron stores (e.g., rapid growth, pregnancy, menstruation) or in settings of low dietary iron intake or inefficient iron uptake (e.g.
 (IDA Ida (ē`dä), city (1990 pop. 91,859), Nagano prefecture, central Honshu, Japan, on the Tenryu River. It is an agricultural market and railway junction. ) around the world. Supplefer Sprinkles contain iron, vitamin C vitamin C
 or ascorbic acid

Water-soluble organic compound important in animal metabolism. Most animals produce it in their bodies, but humans, other primates, and guinea pigs need it in the diet to prevent scurvy.
 and other nutrients and are packaged in a single-dose sachet sa·chet  
n.
A small packet of perfumed powder used to scent clothes, as in trunks or closets.



[French, from Old French, diminutive of sac, bag, from Latin saccus; see sack
 to be "sprinkled" onto food. The report, published on February 28 and titled "'Home-fortification' with Micronutrient mi·cro·nu·tri·ent
n.
A substance, such as a vitamin or mineral, that is essential in minute amounts for the proper growth and metabolism of a living organism.
 Sprinkles - A New Approach for the Prevention and Treatment of Nutritional Anemias," was written by Stanley Zlotkin, M.D., a senior scientist in The Hospital for Sick Children Research Institute in Toronto, Canada. The report's findings are being made available for Anemia Awareness Week in Canada (March 24-28, 2003), which focuses on raising awareness of anemia as a potentially serious condition.

"Iron-deficiency anemia continues to be a pervasive and largely unaddressed global health problem, affecting more than two billion people or roughly one third of the world's population," said Dr. Zlotkin, a professor of Paediatrics and Nutritional Sciences at the University of Toronto Research at the University of Toronto has been responsible for the world's first electronic heart pacemaker, artificial larynx, single-lung transplant, nerve transplant, artificial pancreas, chemical laser, G-suit, the first practical electron microscope, the first cloning of T-cells, . "In fact, in Canada and the United States The United States and Canada share a unique legal relationship. U.S. law looks northward with a mixture of optimism and cooperation, viewing Canada as an integral part of U.S. economic and environmental policy. , roughly five percent of children aged one to five suffer from IDA. However, a new breakthrough nutritional supplement called Supplefer Sprinkles is working to address this worldwide health issue."

Dr. Zlotkin's long-term goal is to make Supplefer Sprinkles a globally available option for infants and children to aid in the reduction of IDA. "This breakthrough is important for the health and livelihood of children in developing countries," Dr. Zlotkin said. "The H.J. Heinz Company Foundation is funding Sprinkles projects over three years. In addition, the Heinz Company is providing technical assistance and significant financial support."

Supplefer Sprinkles are inexpensive to produce and are packaged in a single-dose sachet that does not require special measuring or handling. Each sachet is designed to be sprinkled or stirred into any food, including rice, barley, congee or porridge, without affecting color or taste. Parents are encouraged to use one packet daily. Supplefer Sprinkles offer an alternative to iron drops, long-known for low compliance since they have a metallic taste, may cause abdominal pain and can stain teeth.

"Heinz, as one of the world's largest producers of single-serve sachets, is well positioned to provide assistance on manufacturing, distribution and commercial sustainability of Supplefer Sprinkles globally," said F. Kerr Dow, Ph.D., chief scientist and vice president - nutrition and technical affairs for Heinz. "This worldwide initiative is backed by a number of government agencies, humanitarian organizations, Heinz international businesses and employees, and pro bono Short for pro bono publico [Latin, For the public good]. The designation given to the free legal work done by an attorney for indigent clients and religious, charitable, and other nonprofit entities.  assistance from our suppliers and consultants."

"It is important for public and private institutions to work together to develop health interventions that are both feasible and sustainable," Dr. Zlotkin said. "Our partnership with Heinz is a humanitarian initiative that appropriately links industry and public health in reducing a major global childhood problem such as iron-deficiency anemia."

The Sprinkles research program is being supported by a CDN (Content Delivery Network) A system of distributed content on a large intranet or the public Internet in which copies of content are replicated and cached throughout the network.  $1.2 million grant from the H.J. Heinz Company Foundation to The Hospital for Sick Children Foundation. The research describing the development of the micronutrient sprinkles was supported by grants from USAID's OMNI OMNI Omnidirectional
OMNI Organising Medical Networked Information
OMNI Opportunities for Micronutrient Interventions Project
OMNI Operating Missions as a Node on the Internet (NASA networking project) 
 Research Program through the Human Nutrition Institute of the ILSI ILSI International Life Sciences Institute
ILSI Incorporated Law Society of Ireland
 Research Foundation, the Micronutrient Initiative (Canada), and Canadian Institutes of Health Research Canadian Institutes of Health Research (CIHR) is the major federal agency responsible for funding health research in Canada. It is the successor to the Medical Research Council of Canada.  (CIHR CIHR Canadian Institutes of Health Research
CIHR Cambodian Institute of Human Rights
).

Dr. Zlotkin owns the intellectual property rights to Sprinkles. The H.J. Heinz Company Ltd is supporting the technical development of the sprinkles on a cost-recovery basis.

Sprinkles Studies

Dr. Zlotkin's research group developed Supplefer Sprinkles as a strategy to reduce global childhood anemia. Numerous studies have been initiated and are underway around the world to evaluate both their efficacy and acceptance:

Efficacy Studies
-- Ghana, West Africa - Efficacy studies were conducted in Ghana, West Africa, between 1998-2001. In these studies, Supplefer Sprinkles were shown to successfully treat anemia among 60-75 percent of infants within two months. In addition, Supplefer Sprinkles also were shown to be well tolerated by infants with few side effects and were well accepted by caregivers who found them easy to use.

-- Canada's First Nations and Inuit populations - With support from Health Canada, Dr. Zlotkin is assessing the efficacy of Supplefer Sprinkles among the First Nations and Inuit populations of Canada where the prevalence of IDA is as high as 32 percent. Trials are underway in Northern Canada and in communities where iron-rich foods are expensive and not readily available.


Acceptance Studies

-- Mongolia - Currently, in partnership with World Vision Canada,

Sprinkles' acceptance and distribution is being evaluated with

more than 13,000 young children in Mongolia. This 18-month

program will conclude in September 2003, and due to the

initial program's success in Mongolia, both UNICEF UNICEF (y`nĭsĕf'), the United Nations Children's Fund, an affiliated agency of the United Nations.  and the

Ministry of Health in Mongolia are actively pursuing

registration of Sprinkles so that nationwide scale-up can be

planned and executed.

-- China, Ghana, India, Mongolia and Pakistan - As an important

component of research, the acceptability of Supplefer

Sprinkles by other caregivers and children was evaluated in

Ghana and China and will continue to be evaluated in ongoing

projects in Mongolia, India and Pakistan. To date, parents

have found the sachets easy to use and more acceptable than

drops.

Anemia Facts

According to the World Health Organization (WHO), iron deficiency affects two-thirds of children in most developing nations. IDA, a result of low iron intake from the diet or losses of blood from parasitic infections, is a leading cause of morbidity and mortality Morbidity and Mortality can refer to:
  • Morbidity & Mortality, a term used in medicine
  • Morbidity and Mortality Weekly Report, a medical publication
See also
  • Morbidity, a medical term
  • Mortality, a medical term
 worldwide. IDA can lead to low hemoglobin levels, which carries oxygen to cells and tissues in the body. Numerous studies have demonstrated that even moderate anemia (hemoglobin less than 100 g/L) is associated with depressed mental and motor development in children that may not be reversible.

About the H.J. Heinz Company Foundation

Established in 1951, the H.J. Heinz Company Foundation is committed to promoting the health and nutritional needs of children and families worldwide. The foundation donates funds to develop and strengthen organizations dedicated to human service, youth & education, women & diversity, civic endeavors, the arts, and quality of life. For more information, visit http://www.heinz.com.

About Heinz

ABOUT HEINZ: H. J. Heinz Company H. J. Heinz Company (NYSE: HNZ), commonly known as Heinz, famous for its "57 Varieties" slogan, is a processed food product company with its headquarters in Pittsburgh, Pennsylvania, in the United States of America.  is one of the world's leading processors and marketers of high-quality ketchup, condiments, sauces, meals, soups, snacks and infant foods through all retail and foodservice channels. A host of favorite brands, such as Heinz(R) ketchup, Ore-Ida(R) french fries, Boston Market(R) and Smart Ones(R) meals and Plasmon(R) baby food are the growth drivers in Heinz's two strategic global segments: Meal Enhancers and Meals & Snacks. Heinz's 50 companies have number-one or number-two brands in 200 countries, showcased by the Heinz(R) brand, a global consumer icon with $2.5 billion in annual sales. Fourteen additional brands, each with more than $100 million in annual sales, generate a further $2.6 billion. Information on Heinz is available at www.heinz.com/news.
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Publication:Business Wire
Geographic Code:9MONG
Date:Mar 26, 2003
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