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Heartburn drugs safe for foetuses, says Israeli study.

Byline: ANI

Washington, Oct 8 (ANI): A new study done by Israeli scientists has shown that heartburn drugs are safe for the foetus.

The study, conducted by researchers at the Ben-Gurion University of the Negev The university is mandated to promote development of the Negev region, inspired by the vision of Israel's first Prime Minister, David Ben-Gurion, who believed that the country's future lay in the relatively undeveloped south. , Israel, has been published in the Journal of Clinical Pharmacology.

According to the new findings H2 blocker drugs like Famotidine, Cimetidine cimetidine /ci·met·i·dine/ (si-met´i-den) a histamine H2 receptor antagonist, which inhibits gastric acid secretion; used as the base or the monohydrochloride salt in the treatment and prophylaxis of gastric or duodenal ulcers,  and Ranitidine ranitidine /ra·ni·ti·dine/ (rah-ni´ti-den) a histamine H2 receptor antagonist, used as the hydrochloride salt to inhibit gastric acid secretion in the treatment of gastric and duodenal ulcer, gastroesophageal reflux disease, and , administered to pregnant women for reducing acid influx can be safely used.

The H2 blockers are the most commonly used medication to relieve acid reflux symptoms of heartburn, regurgitation regurgitation /re·gur·gi·ta·tion/ (re-ger?ji-ta´shun)
1. flow in the opposite direction from normal.

2. vomiting.
 and trouble swallowing in pregnant women.

Dr. Rafael Gorodischer, professor emeritus at Ben-Gurion University of the Negev said: "Of the vast majority of medications approved for use, there is insufficient data from human studies to determine whether the benefits of therapy exceed the risk to the fetus.

"Medicines are approved for use only after there is sufficient scientific evidence demonstrating the drug safety and effectiveness for its intended uses."

"Exposure to H2 blockers among this group was not associated with significantly increased risks of major congenital malformations. The results were unchanged when therapeutic abortions of exposed fetuses were included in the analysis.

Also, infants exposed in utero had no increased risk of perinatal mortality, low birth weight or premature birth," said Dr. Amalia Levy of the BGU BGU Ben Gurion University (Beer-Sheva, Israel)
BGU Bowling Green University
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 Faculty of Health Sciences. (ANI)

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Publication:Asian News International
Date:Oct 21, 2009
Words:236
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