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Handbook of Pharmaceutical Additives-Third Edition Describes More Than 5300 Trade Name Products and 4000 Generic Chemicals and Materials.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c70525) has announced the addition of Handbook of Pharmaceutical Additives-Third Ed. to their offering.

The Handbook of Pharmaceutical Additives, Third Edition has been extensively updated from the previous edition, which was published in 2002. It describes more than 5300 trade name products and 4000 generic chemicals and materials, available from worldwide manufacturers, that function as pharmaceutical additives.

Pharmaceutical additives are defined in this reference as secondary ingredients present in both prescription and over-the-counter drug over-the-counter drug A therapeutic agent that does not require a prescription, which the FDA feels can be safely self-prescribed by non-physicians. Cf Prescription drug, Under-the-counter.  formulations and contributing in one or more of the following ways:

- improving consumption ease of the dosage form A dosage form is the physical form of a dose of medication, such as a capsule or injection. The route of administration is dependent on the dosage form of a given drug.  by masking unpleasant odor, improving palatibility or appearance of the active ingredient An active ingredient, also active pharmaceutical ingredient (or API), is the substance in a drug that is pharmaceutically active. Some medications may contain more than one active ingredient. .

- enabling or enhancing the delivery of the drug or medicine that is available in a variety of dosage forms (i.e., oral; topical, ophthalmic, and otic; suppositories suppositories,
n.pl solid capsules made of materials that melt at body temperature and are used to deliver medicinal substances into the rectum.
; injectables; inhalants inhalants,
n.pl 1. chemical vapors that are inhaled for their mind-altering effects.
2. in herbology, volatile herbal compounds that are delivered by holding a soaked pad to the nose and mouth, by placing the herbs in steaming water, or
) and thus improving its efficacy, control of bioavailability bioavailability /bio·avail·a·bil·i·ty/ (bi?o-ah-val?ah-bil´i-te) the degree to which a drug or other substance becomes available to the target tissue after administration.

bi·o·a·vail·a·bil·i·ty
n.
, uniformity, and/or flow characteristics

- increasing the stability of active ingredients

- acting as a filler or diluent diluent /dil·u·ent/ (dil´oo-int)
1. causing dilution.

2. an agent that dilutes or renders less potent or irritant.


dil·u·ent
adj.
Serving to dilute.

n.
 so that an adequate amount of material is available to properly fill a dosage form

- acting as an antimicrobial or antioxidant antioxidant, substance that prevents or slows the breakdown of another substance by oxygen. Synthetic and natural antioxidants are used to slow the deterioration of gasoline and rubber, and such antioxidants as vitamin C (ascorbic acid), butylated hydroxytoluene  to extend the shelf life of the active ingredient

Thus, the definition of pharmaceutical additives for the purpose of this work encompasses excipients excipients,
n.pl all the constituents of a remedy that lack medicinal properties. See also adjuvant, auxiliary substance, and vehicle.
, synergists, or chemicals that substantively contribute to the effectiveness of the active ingredient. Entries for both trade names and chemicals contain extensive information gathered from worldwide manufacturers, distributors, trade journals, government documents, and other reference sources.

Both the Handbook of Pharmaceutical Additives, Third Edition and the software version centralize and integrate information on these chemicals and materials thereby serving as an essential guide to product managers, formulation scientists, quality controllers, ingredient chemists, pharmacists, physicians, and consumers.

Content Outline:

Book and Software:

PART I-Trade Name Reference

Trade Name Reference contains over 5300 alphabetical entries of trade name pharmaceutical additive products with extensive profiles of each product listed.

Software features: Full-text Search A search that compares every word in a document, as opposed to searching an abstract or a set of keywords associated with the document. Word processors and text editors contain full-text search functions that let you find a word or phrase anywhere in the document.  with Boolean operator support

Keyword Indexes: Comprehensive Index, Trade Name X-Ref, Generic Chemical X-Ref, Manufacturers X-Ref, CAS X-Ref, EINECS/ELINCS X-Ref, Functional/Applications X-Ref.

Hyperlinking: Trade names manufacturers to Manufacturers Directory and websites; Generic chemicals to Generic Products, Trade Name Cross-Reference

Part II-Chemical Component Cross-Reference

Chemical Component Cross-Reference contains more than 4000 pharmaceutical chemicals/materials that are either contained in the trade name products profiled in Part I or are generic chemicals used as pharmaceutical additive ingredients. Each entry includes, wherever possible, its synonyms, CAS number, EINECS EINECS European Inventory of Existing Commercial Chemical Substances  number/ELINCS, FEMA FEMA,
n.pr See Federal Emergency Management Agency.
 number, UN/DOT number, molecular and empirical formulas, chemical properties, functions and applications, toxicology, precautions, use levels, regulatory information, and manufacturers and distributors of the chemical. All chemical/material synonyms are cross-referenced back to the main entry. The chemical monograph entries also contain a listing of the trade name products that are either equivalent to the chemical entry or contain this chemical as one of its ingredients.

Software features: Full-text Search with Boolean operator support

Keyword Indexes: Comprehensive Index, Trade Name X-Ref, Generic Chemical X-Ref, Manufacturers X-Ref, CAS X-Ref, EINECS/ELINCS X-Ref, Functional/Applications X-Ref., Molecular Formula Dir.

Hyperlinking: Trade names to Trade Name Reference, generic manufacturers to Manufacturers Directory, all cross-references (synonyms) to main entries

Part III-Functional/Application Index

Functional/Application Index is a powerful tool for locating the trade names and chemicals based on their function and application. By searching for key functional words related to pharmaceutical additives such as anticaking agents, binders, colorants, disintegrants, emulsifiers, encapsulants, fillers, flavors, gellants, in specific application areas such as tablets, capsules, inhalants, ointments ointments,
n.pl semisolid, non–water-based treatments that are not water-soluble and that create protective films to prevent dehydration of the skin.
, suppositories, etc., the user is directed to the trade names and/or chemicals that have that specific functional/application attribute. The generic component names are distinguished from the trade names by italic type in the book and color in the software.

Software features: Full-text Search with Boolean operator support

Hyperlinking: Trade names to Trade name Section, Generics to Generic Chemical section

Part IV-Manufacturers Directory

Detailed contact information for the more than 3000 worldwide manufacturers and their branches of trade name products and chemical components that are referenced in this handbook. Wherever possible, telephone, telefax The European term for a fax machine. , toll-free numbers, e-mail and internet addresses (functional in the software), and complete mailing addresses are included for each manufacturer.

Software features: Full-text Search with Boolean operator support

Keyword Indexes: Comprehensive Index, Manufacturers Dir., Manufacturers X-Ref., MFG MFG Manufacturing
MFG Manufacturer
MFG Mit Freundlichen Grüßen (German: With Best Regards)
MfG Mitfahrgelegenheit (German)
MFG Marithe Francois Girbaud (French clothing company) 
 Web&Email Directory

Hyperlinking: All cross-references (alternate names) to main entries, Manufacturer Web sites, Manufacturer Email

For more information visit http://www.researchandmarkets.com/reports/c70525.
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