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Giant-cell reparative granuloma.


The characteristics of giant-cell reparative granulomas are similar to those of giant-cell tumors except that they are usually related to pre-existing trauma. Microscopically, giant-cell reparative granulomas feature a zonal reactive inflammatory pattern in which multinucleated multinucleated

characterized by having more than one nucleus per cell.


multinucleated giant cell
see giant cell.
 giant cells and hemosiderin-laden macrophages surround areas of hemorrhage, as in the case presented here. Osteoid osteoid /os·te·oid/ (os´te-oid)
1. resembling bone.

2. the organic matrix of bone; young bone that has not undergone calcification.


os·te·oid
adj.
Resembling bone.
 formation can be seen in reparative granulomas it is usually absent in true giant-cell tumors.

Giant-cell reparative granulomas are more often found in the mandible, max illa, and sinonasal cavity, where they can cause local expansion and destruction. [1] In this case, a 48-year-old woman had an expansile ex·pan·sile  
adj.
Of, relating to, or capable of expansion.

Adj. 1. expansile - (of gases) capable of expansion
expandable, expandible, expansible
 mass in the sinonasal cavity on the right. It was detected on physical examination and on computed tomography (CT) (figure).

From the Department of Radiology, Louisiana State University Louisiana State University and Agricultural and Mechanical College, generally known as Louisiana State University or LSU, is a public, coeducational university located in Baton Rouge, Louisiana and the main campus of the Louisiana State University System.  Health Science Center, New Orleans (Dr. Palacios), and the Department of Radiology and Otolaryngology, University of Illinois University of Illinois may refer to:
  • University of Illinois at Urbana-Champaign (flagship campus)
  • University of Illinois at Chicago
  • University of Illinois at Springfield
  • University of Illinois system
It can also refer to:
 Medical Center, Chicago (Dr. Valvassori).

Reference

(1.) Mafee MF, Carter BL. Nasal cavity and paranasal sinuses. In: Valvassori GE, Mafee MF, Carter BL, eds. Imaging of the Head and Neck. New York: Thieme Medical Publishcr5, 1995:248-328.
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Author:Valvassori, Galdino
Publication:Ear, Nose and Throat Journal
Article Type:Brief Article
Geographic Code:1USA
Date:Sep 1, 2000
Words:181
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