Germline stem cells.9781603272131 Germline stem cells stem cells, unspecialized human or animal cells that can produce mature specialized body cells and at the same time replicate themselves. Embryonic stem cells are derived from a blastocyst (the blastula typical of placental mammals; see embryo), which is very young . Ed. by Steven X. Hou and Shree Ram Singh. Humana Press Inc. 2008 273 pages $99.50 Hardcover Methods in molecular biology molecular biology, scientific study of the molecular basis of life processes, including cellular respiration, excretion, and reproduction. The term molecular biology was coined in 1938 by Warren Weaver, then director of the natural sciences program at the Rockefeller ; 450 RC952 These cells, the source of human and animal reproduction, may eventually protect endangered species, manage commercial livestock, affect human fertility, and even treat testicular testicular /tes·tic·u·lar/ (tes-tik´u-lar) pertaining to a testis. tes·tic·u·lar adj. Of or relating to a testicle or testis. testicular pertaining to the testis. and ovarian tumors. The contributors of these 16 articles focus first on the identification and regulation of germline stem cells in model organisms, describing the development of germline stem cells in Drosophilia, analyzing the C. elegans germline stem cell region, giving immunohistological techniques for study, describing how to use genetic tools to trace cell lineage and gene manipulation, determining the structured polarity of male germline stem cells, conducting high-resolution light microscopic characterization of spermatogonia, identifying and characterizing spermatogonial subtypes, attaining epigenetic epigenetic /epi·ge·net·ic/ (-je-net´ik) 1. pertaining to epigenesis. 2. altering the activity of genes without changing their structure. control in male germ cells and maintaining spermatogonial germ cells in vivo and in vitro. The remaining seven articles detail protocols of in vitro culture and applications, including spermatogonial germ cell transplantation, ectopic ectopic /ec·top·ic/ (ek-top´ik) 1. pertaining to ectopia. 2. located away from normal position. 3. arising from an abnormal site or tissue. ec·top·ic adj. grafting of mammalian testis testis (tĕs`tĭs) or testicle (tĕs`tĭkəl), one of a pair of glands that produce the male reproductive cells, or sperm. tissue, and deriving mouse spermatogonial stem cell lines. ([c]20082005 Book News, Inc., Portland, OR) |
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