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Germ zapper.


You've probably experienced the power of antibiotics. These amazing a·maze  
v. a·mazed, a·maz·ing, a·maz·es

v.tr.
1. To affect with great wonder; astonish. See Synonyms at surprise.

2. Obsolete To bewilder; perplex.

v.intr.
 medicines kill the bacteria that give you strep throat Strep Throat Definition

Streptococcal sore throat, or strep throat as it is more commonly called, is an infection of the mucous membranes lining the pharynx. Sometimes the tonsils are also infected (tonsillitis).
 and other infections. Usually, you start feeling better after a day or two of treatment.

Antibiotics have become so widely used, however, that many bacteria have developed ways to survive treatment. And when antibiotics stop working, sick people end up getting sicker. Tens of thousands of people die each year as a result.

Now, scientists at Merck Research Laboratories in Rahway, N.J., may have found a new weapon against antibiotic-resistant bacteria. Lab tests in mice show that a compound called platensimycin attacks--and kills--certain bacteria in a new way.

Antibiotics were developed more than 50 years ago, and most types currently available work the same way as the early kind did. They attack bacteria cell walls. Or, they disable To turn off; deactivate. See disabled.  bacteria by knocking out the parts of the cell that make DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 and proteins.

Platensimycin takes a different approach. It attacks an enzyme that bacteria need to build and maintain membranes in their cells. Enzymes are types of proteins that make chemical reactions This is the 18th episode of television drama Men in Trees. It originally aired on June 25, 2007 on the TV2 network in New Zealand as a continuation of season 1. Recap
Marin and Cash have a stew cook off, she admits his is better than hers.
 happen more quickly.

The neat thing about platensimycin is that it exists in nature. It is, in fact, the fourth natural compound found that targets the same enzyme. It's also, by far, the most powerful of the four compounds.

"Nature is telling us again and again that if you want to go after bacteria, go after this enzyme," says Charles O. Rock, a biochemist at St. Jude Children's Research Hospital St. Jude Children's Research Hospital, founded in 1962, is a leading pediatric treatment and research facility focused on children's catastrophic diseases. It is located in Memphis, Tennessee.

In 1996, Peter Doherty, Ph.D., of St.
 in Memphis, Tenn.

The Merck scientists found platensimycin by sorting through about 250,000 natural compounds. The search led to platensimycin, which is a small molecule made by a bacterium that lives in the soil in South Africa South Africa, Afrikaans Suid-Afrika, officially Republic of South Africa, republic (2005 est. pop. 44,344,000), 471,442 sq mi (1,221,037 sq km), S Africa. . Scientists aren't yet sure whether platensimycin will work as a drug in people. Still, the research is another example of how good nature can be at solving problems.--E. Sohn
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Author:Sohn, Emily
Publication:Science News for Kids
Article Type:Brief article
Geographic Code:1USA
Date:May 24, 2006
Words:318
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