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Genes may impact your time in dreamland.


The amount of sleep needed each night may depend less on fluffy pillows than a single genetic mutation, according to research published this August. A team of scientists claim they have identified a gene that regulates the optimum amount of human sleep each individual needs, explaining why after 6 hours of slumber one person may awake reborn, while another is like the living dead. The study, published in Science last month, identified a mother and daughter pair who needed well below the 8.5 hours a night that doctors say is a must for long-term well-being. Blood tests from the rested pair showed a mutation in their DEC2 gene, which has previously been implicated in the control of circadian rhythms - the cycles that regulate the daily patterns of human behaviour. Lead scientist Ying Hui Fu, a professor of neurology at the University of California, said her team then tested their findings on genetically modified mice and fruit flies. The animals were observed scampering around in the dark more and sleeping less. Fu said the observations 'could provide an explanation for why human subjects with the mutation are able to live unaffected by short amounts of sleep throughout their lives'. It is still unclear whether the mutation affects sleep quantity alone or also wakefulness.

COPYRIGHT 2009 South African Medical Association
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2009 Gale, Cengage Learning. All rights reserved.

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Title Annotation:International
Author:Bateman, Chris
Publication:CME: Your SA Journal of CPD
Article Type:Brief article
Geographic Code:6SOUT
Date:Sep 1, 2009
Words:213
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