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The AIDS Clinical Trials Unit (ACTU ACTU Australian Council of Trade Unions
ACTU AIDS Clinical Trials Unit (Washington University Medical Center, St. Louis, Missouri)
ACTU Association of Catholic Trade Unionists
ACTU Australian Capital Territory Union
) at The University of Texas Medical Branch "UTMB" redirects here. For other system schools, see University of Texas System.
The University of Texas Medical Branch (UTMB) is a component of the University of Texas System located in Galveston, Texas, about 50 miles (80 km) southeast of downtown Houston.
 (UTMB UTMB University of Texas Medical Branch ) in Galveston is conducting several clinical trials. A few of these are listed below. For more information, contact the ACTU at 409-747-0214 or toll free at 877-324-2288.

* ACTG A5163: Bone loss is a problem associated with HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States.  infection and possibly HIV treatment. This study will look at the effectiveness of alendronate alendronate /alen·dro·nate/ (ah-len´dro-nat) a bisphosphonate calcium-regulating agent used in the form of the sodium salt to inhibit the resorption of bone in the treatment of osteitis deformans, osteoporosis, and hypercalcemia related  (brand name: Fosamax) plus calcium and vitamin D for treating bone loss in people with HIV. To participate in this study, you must have a viral load less than 1000, a T cell count greater than 100, and be on HIV medications for at least 12 weeks with good virus control. Also, you should not plan on changing your diet or exercise habits for the 48 weeks of the study.

* ACTG 5093: Depo-medroxyprogesterone or DMPA (brand name: Depo-Provera) is a hormone treatment for women that helps regulate the menstrual cycle and is sometimes used for birth control, among other purposes. This study will look for possible drug interactions with HIV drugs. To participate in this 12-week study, females with HIV must have a viral load less than 10,000 and T cells greater than 200. Also, you cannot have taken DMPA within 180 days before the study, and you cannot have been through menopause. DMPA, but not HIV medications, will be provided for this study.

* ACTG A5127: This study will look at the treatment of hepatitis B in HIV+ patients for whom Epivir will not work because of hepatitis B drug resistance. Participants will be given adefovir (brand name: Hepsera) or Viread to treat the hepatitis B. You must be co-infected with HIV and hepatitis B, with an HIV viral load HIV viral load AIDS A measure of the amount of HIV RNA in blood, expressed as number of copies/mL of plasma. See AIDS, HIV.  less than 10,000 and a hepatitis B viral load more than 1 million. You cannot have hepatitis C or hepatitis D. You should be taking HIV therapy with good virus control; you should not be taking Ziagen (which is also in Trizivir).
COPYRIGHT 2003 The Center for AIDS: Hope & Remembrance Project
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2003 Gale, Cengage Learning. All rights reserved.

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Title Annotation:Clinical Trial Information
Publication:HIV Treatment: ALERTS!
Date:Oct 1, 2003
Words:329
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