GTx to Present at the UBS Global Life Sciences Conference.

MEMPHIS, Tenn. -- GTx, Inc. (Nasdaq: GTXI) announced today that management will present a company overview on September 25 at the UBS Global Life Sciences Conference in New York City. The GTx presentation will begin at 4:00 p.m. Eastern Time. A simultaneous webcast of the presentation will be accessible from the investor relations section of the GTx website at www.gtxinc.com. An archived replay of the presentation will be available on the company website until October 9.

About GTx

GTx, headquartered in Memphis, Tenn., is a biopharmaceutical company dedicated to the discovery, development, and commercialization of small molecules that selectively target hormone pathways to treat cancer, osteoporosis and bone loss, muscle wasting and other serious medical conditions. GTx is developing ACAPODENE[R] (toremifene citrate), a selective estrogen receptor modulator, or SERM, in two separate clinical programs in men: first, a pivotal Phase III clinical trial for the treatment of serious side effects of androgen deprivation therapy for advanced prostate cancer, and second, a pivotal Phase III clinical trial for the prevention of prostate cancer in high risk men with high grade prostatic intraepithelial neoplasia, or PIN. GTx has licensed to Ipsen Limited exclusive rights in Europe to develop and commercialize ACAPODENE. GTx also is developing Ostarine[TM], a first-in-class selective androgen receptor modulator, or SARM. GTx has initiated a Phase IIb Ostarine clinical trial for the treatment of cancer cachexia. GTx plans to initiate a Phase IIb Ostarine clinical trial for the treatment of chronic kidney disease muscle wasting by the end of 2007. GTx believes that Ostarine also has the potential to treat a variety of other indications associated with muscle wasting and bone loss including sarcopenia and osteoporosis. GTx is also developing two other product candidates, GTx-838, another GTx SARM, for the treatment of sarcopenia, and GTx-878, an estrogen receptor beta agonist for the treatment of benign prostatic hyperplasia and chronic prostatitis. GTx is planning to file an Investigational New Drug application (IND) with the FDA for GTx-838 by year end 2007 and to file an IND for GTx-878 during 2008.

Forward-Looking Information is Subject to Risk and Uncertainty

This press release contains forward-looking statements based upon GTx's current expectations. Forward-looking statements involve risks and uncertainties. GTx's actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of these risks and uncertainties, which include, without limitation, the risks that (i) GTx will not be able to commercialize its product candidates if clinical trials do not demonstrate safety and efficacy in humans; (ii) GTx may not be able to obtain required regulatory approvals to commercialize its product candidates; (iii) GTx's clinical trials may not be completed on schedule, or at all, or may otherwise be suspended or terminated; and (iv) GTx could utilize its available cash resources sooner than it currently expects and may be unable to raise capital when needed, which would force GTx to delay, reduce or eliminate its product development programs or commercialization efforts. You should not place undue reliance on these forward-looking statements, which apply only as of the date of this press release. GTx's quarterly report on form 10-Q filed with the U.S. Securities and Exchange Commission on August 1, 2007, contains under the heading "Risk Factors," a more comprehensive description of these and other risks to which GTx is subject. GTx expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.