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GNI Identifies Important Reuglator and Associated Signaling Cascade in Human Immunological Disorders.


Tokyo, Japan, Sept 20, 2006 - (JCN JCN Japan Corporate News
JCN Journal of Cognitive Neuroscience
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JCN joint communications network (US DoD) 
) - GNI GNI Gross National Income
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 and its Chinese affiliate Shanghai Genomics announced September 15 that they have identified an important regulator and its associated signaling cascade in X-linked lymphoproliferative disease (XLP), a human immunological disorder.

XLP, also known as Duncan's syndrome, is an inherited genetic defect that causes immune system dysfunction in response to some viral infections. The disorder prevents patients from generating functional SAP proteins, which can subsequently cause a diverse range of immune system abnormalities and in many cases lead to the development of lymphoid tumors and fatality.

Due to the severe clinical manifestations found in XLP patients, intense efforts had recently focused on elucidating the signaling mechanism used by SAP to regulate in cells involved in immune surveillance against cancers.

The findings of the research are to be published by the Proceedings of the National Academy of Sciences The Proceedings of the National Academy of Sciences of the United States of America, usually referred to as PNAS, is the official journal of the United States National Academy of Sciences.  of the United States of America UNITED STATES OF AMERICA. The name of this country. The United States, now thirty-one in number, are Alabama, Arkansas, Connecticut, Delaware, Florida, Georgia, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Mississippi, Missouri, New Hampshire,  (PNAS PNAS Proceedings of the National Academy of Sciences
PNAS Phosphate:Na + Symporter
PNAS Pensacola Naval Air Station
PNAS Philippine National Airsoft Society
), one of the world's most-cited multidisciplinary scientific serials, during the week of September 11, 2006.

Copyright [c] 2006 Japan Corporate News Network. All rights reserved.
COPYRIGHT 2006 Japan Corporate News Network K.K.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:JCNN News Summaries
Date:Sep 20, 2006
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