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GENESIS Network's PGD Study Published in Fertility and Sterility; Study Offers Women 38+ Years New Data Supporting Increased Chances for Pregnancy Success.


Business Editors/Health/Medical Writers

IRVINE, Calif.--(BUSINESS WIRE)--Sept. 10, 2003

The GENESIS Network for Reproductive Health Within the framework of WHO's definition of health[1] as a state of complete physical, mental and social well-being, and not merely the absence of disease or infirmity, reproductive health, or sexual health/hygiene , an independent group of nationally noted fertility specialists, announced its breakthrough study published in Fertility and Sterility, a leading international medical journal.

According to according to
prep.
1. As stated or indicated by; on the authority of: according to historians.

2. In keeping with: according to instructions.

3.
 Dr. Lawrence Werlin, the study's principal investigator and the co-founder of GENESIS, the study gives women in high-risk categories, including women 38 years and older, new answers regarding their chances for increasing pregnancy success through in-vitro fertilization (IVF IVF in vitro fertilization.

IVF
abbr.
in vitro fertilization


IVF 1 In vitro fertilization, see there 2. Intravascular fluid
).

The study analyzes Preimplantation Genetic Diagnosis preimplantation genetic diagnosis: see embryo biopsy.  (PGD PGD Preimplantation Genetic Diagnosis
PGD Postgraduate Diploma
PGD Phosphogluconate Dehydrogenase
PGD Policy for Global Development
PGD PhpGmailDrive (file sharing utility)
PGD Product Group (US Marine Corps) 
), a therapeutic and diagnostic genetic testing Genetic Testing Definition

A genetic test examines the genetic information contained inside a person's cells, called DNA, to determine if that person has or will develop a certain disease or could pass a disease to his or her offspring.
 tool that allows for the analysis and transfer of healthy embryos back to the uterus. The study concludes that PGD can facilitate a successful pregnancy and avoid IVF failures from chromosomal imbalances.

"PGD expands our ability to explore IVF failure for these seemingly healthy women," Dr. Werlin said. "Through PGD we are able to assess the chromosomal makeup of embryos in infertile in·fer·tile
adj.
Not capable of initiating, sustaining, or supporting reproduction.


infertile,
adj unable to produce offspring.
 women 38+ years. Our findings offer women a greater understanding of how to proceed through IVF. The likelihood is that women of Advanced Maternal Age maternal age,
n the age of the mother at the period of conception.
 will experience a repetitive phenomenon and continue producing abnormal or non-transferable embryos."

A total of 21 women from 38 to 44 years were evaluated. The data concluded that 70% of the embryos in this group of women were abnormal. Of these patients, 30% had no healthy embryos to transfer.

"Publication of the GENESIS study led by Werlin will enable us to further educate health specialists and document issues revolving around PGD's role and its ability to assist high-risk patients achieve pregnancy success or select alternative options to consider using such as donor eggs or embryos," said Alan DeCherney, M.D., Editor-In-Chief, Fertility and Sterility.

Fertility and Sterility(R) is the official journal for leading organizations such as the American Society for Reproductive Medicine and Society for Reproductive Endocrinology. Articles selected for publication must feature original scientific data from clinical and laboratory research.

Dr. Werlin is a leader in reproductive technology, research, education, and patient services and the founder and director of Coastal Fertility Medical Center in Irvine.

For more information on the study, visit www.coastalfertility.com.

Note to Editors: For interviews with patients involved in the study or Dr. Werlin call 714-573-0842.
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No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2003, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Sep 10, 2003
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