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GE Healthcare Signs Exclusive Distribution Agreement for DiscoveRx HitHunter cAMP Assays.


CHALFONT ST GILES, United Kingdom -- GE Healthcare GE Healthcare is a $18 billion (USD) unit of General Electric (GE). It employs more than 46,000 people worldwide and is headquartered in Chalfont St. Giles, Buckinghamshire, United Kingdom. GE Healthcare is the first GE business segment headquartered outside the United States.  and DiscoveRx (Fremont, CA) have entered into an exclusive distribution agreement for all HitHunter(TM) cAMP Enzyme Fragment Complementation Complementation (genetics)

The complementary action of different genetic factors. The term usually implies two homologous chromosomes or chromosome sets, each defective because of mutation and unable by itself to promote the normal development or metabolism of
 (EFC EFC Expected Family Contribution
EFC Expect(ed) Further Clearance
EFC Evangelical Fellowship of Canada
EFC Evangelical Free Church
EFC Eastfield College
EFC Everton Football Club
EFC Electronic Fee Collection
)-based assays, designed for high throughput, non-radioactive screening of compounds in drug discovery.

"We are very pleased to announce the expansion of our agreement with DiscoveRx, which grants GE Healthcare exclusive global distribution rights to HitHunter cAMP assays and provides our customers with more options for cutting edge, high throughput screening technology. We are already known for our SPA screening products; adding the DiscoveRx portfolio allows us to offer a more comprehensive suite of screening technologies to our customers, combined with the high quality and service they have come to expect," says Ger Brophy, general manager of Discovery Sciences, at GE Healthcare.

The agreement not only grants GE Healthcare global exclusivity for DiscoveRx's cAMP assays, it also expands distribution of the company's portfolio of kinase assays, with exclusive distribution in the Asia Pacific region.

HitHunter cAMP assays are homogeneous, non-radioactive, cell-based assays used to screen for G-protein coupled receptor (GPCR GPCR Guanine Nucleotide-Binding Protein-Coupled Receptor
GPCR GTP-binding Protein-Coupled Receptor
) activation in a microplate-based format. GPCRs represent a large class of membrane proteins A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. More than half of all proteins interact with membranes.  that play an important role in cell signaling Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as  pathways and are important targets for drug discovery.

"DiscoveRx's HitHunter GPCR and kinase products are well accepted by drug discovery customers. We are tremendously excited about this important step forward, which broadens the global access of our HitHunter products through a premier supplier of life science research tools," says Pyare Khanna, Ph.D., CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of DiscoveRx Corp.

About GE Healthcare

GE Healthcare provides transformational medical technologies and services that are shaping a new age of patient care. Our expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, performance improvement, drug discovery, and biopharmaceutical manufacturing technologies is helping clinicians around the world re-imagine new ways to predict, diagnose, inform and treat disease, so their patients can live their lives to the fullest.

GE Healthcare's broad range of products and services enable healthcare providers to better diagnose and treat cancer, heart disease, neurological diseases Noun 1. neurological disease - a disorder of the nervous system
nervous disorder, neurological disorder

disorder, upset - a physical condition in which there is a disturbance of normal functioning; "the doctor prescribed some medicine for the disorder";
, and other conditions earlier. Our vision for the future is to enable a new "early health" model of care focused on earlier diagnosis, pre-symptomatic disease detection and disease prevention. Headquartered in the United Kingdom, GE Healthcare is a $15 billion unit of General Electric Company (NYSE NYSE

See: New York Stock Exchange
:GE). Worldwide, GE Healthcare employs more than 43,000 people committed to serving healthcare professionals and their patients in more than 100 countries. For more information about GE Healthcare, visit our website at www.gehealthcare.com.

About DiscoveRx

Founded in 2000, DiscoveRx is a privately held, venture-backed company headquartered in Fremont, California For the unincorporated community in Yolo County, California, see .
Fremont (IPA: /ˈfriːmɒnt/) is a city in California that was incorporated on January 23, 1956, from the merger of five smaller communities:
, with an additional office in Birmingham, England. DiscoveRx pioneered the use of beta-galactosidase enzyme fragment complementation in biochemical and cell based assays for discovery research and holds extensive intellectual property in this area. DiscoveRx is dedicated to the development and commercialization of innovative solutions to study GPCRs, kinases and other major drug target classes. DiscoveRx HitHunter products have been adopted in pharmaceutical and biotech drug screening initiatives for a number of years. For more information, visit www.discoverx.com
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Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:May 24, 2006
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