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First "Live Case" Transmission of a PFO Closure Procedure Using the Coherex FlatStent PFO Closure System to be Presented at TCT 2007.


Closed circuit satellite broadcast from Germany of this breakthrough procedure is being directed by Principal Investigator, Prof. Horst Sievert sieĀ·vert
n.
Abbr. Sv A unit of ionizing radiation absorbed dose equivalent in the International System of Units, obtained as a product of the absorbed dose measure in grays and a dimensionless factor, stipulated by the International
, M.D.

SALT LAKE CITY & WASHINGTON -- Coherex Medical today announced that physicians attending the Cardiovascular Research Foundation's (CRF CRF
abbr.
chronic renal failure


CRF Chronic renal failure
) nineteenth annual Transcatheter Cardiovascular Therapeutics (TCT TCT The Capital Times (Madison, WI newspaper)
TCT Transcatheter Cardiovascular Therapeutics
TCT The Coroner's Toolkit
TCT Trans Canada Trail
TCT Tcl Core Team
TCT Tsukuba College of Technology (Japan) 
) scientific symposium will have the first opportunity to observe a "live case" PFO PFO Patent Foramen Ovale (defect of the heart)
PFO Paphos, Cyprus - International (Airport Code)
PFO Principal Federal Official (US Departement of Homeland Security) 
 closure procedure using the Coherex FlatStent[TM] PFO Closure System.

The live case is part of the COHEREX-EU CE Mark Study and will be conducted at 9 a.m. (EDT EDT
abbr.
Eastern Daylight Time


EDT Eastern Daylight Time

EDT n abbr (US) (= Eastern Daylight Time) → hora de verano de Nueva York

EDT 
) on Monday, October 22, 2007 at Sankt Katharinen Hospital in Frankfurt, Germany and delivered via closed circuit satellite broadcast in the Main Arena at TCT 2007. Prof. Horst Sievert, M.D. is the Principal Investigator of the COHEREX-EU Study.

"This live case broadcast is a great opportunity for cardiologists to see how the Coherex FlatStent can be used to close a heart defect called a patent foramen ovale patent foramen ovale PFO Cardiology An opening between the left and right atria which allows blood to bypass the lungs in utero; the FO normally closes shortly after birth, but remains open in up to 20%; a PFO is, in absence of other cardiac defects, is of no consequence  (PFO) quickly and easily," said Richard J. Linder, Coherex president and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. . "Approximately 25 percent of all adults have a PFO, which may lead to an increased incidence of stroke or migraine. We believe that we have pioneered a new class of stent that will be used in much the same way as existing stents but with one major exception - the Coherex FlatStent is used to close a cardiac structure instead of opening one. We invite all TCT 2007 attendees to join us in the main arena for this broadcast."

In addition to its first live case transmission, Coherex will hold a special symposium for physicians and medical professionals attending TCT 2007 entitled "The Coherex FlatStent - The Future of PFO Closure." Preceded by a breakfast starting at 6:30 a.m., the Coherex program will be held from 7 a.m. to 8 a.m. on October 22 in Room 144C in the Washington Convention Center The Washington Convention Center has been the name of two convention centers in Washington, D.C. The old Washington Convention Center was located at 909 H Street NW and was in use from 1983 until 2004. .

The specific schedule for the Coherex program is as follows:
[TABLE OMITTED]


TCT 2007 participants interested in attending the Coherex program should contact Phil Carter at 801-231-5297 or pcarter@coherex.com. Interested parties can also visit Coherex Medical at booth #1064 during TCT 2007.

About Patent Foramen Ovale (PFO) Heart Defects

A foramen ovale foramen ovale
n.
An opening in the septum between the right and left atria of the heart, present in the fetus but usually closed soon after birth.
 is a tunnel-like opening between the upper chambers of the heart that allows blood to bypass the lungs and is present in all fetuses. Normally, the foramen ovale closes soon after an infant is born. However, if this opening fails to close naturally after birth the opening is said to remain patent and the condition is called a patent foramen ovale (PFO).

PFO is a common heart defect that occurs in approximately 25 percent of the population. Under certain conditions, a PFO may allow blood to bypass the lungs and shunt directly from the right side of the heart to the left. Since the lungs normally filter all of the blood, this shunt may allow unfiltered Please wikify (format) this article or section as suggested in the Guide to layout and the Manual of Style.
Remove this template after wikifying. This article has been tagged since
 blood clots Blood Clots Definition

A blood clot is a thickened mass in the blood formed by tiny substances called platelets. Clots form to stop bleeding, such as at the site of cut.
 and other components to travel directly to the brain.

There are at least two medical conditions that may benefit from PFO closure: stroke and migraine. According to the Stroke Council of the American Heart Association American Heart Association (AHA),
n.pr a national voluntary health agency that has the goal of increasing public and medical awareness of cardiovascular diseases and stroke, and thereby reducing the number of associated deaths and disabilities.
, approximately 500,000 strokes each year worldwide may be attributable to the presence of a PFO, which represents a potential annual market size of close to $2 billion.

Migraine affects approximately 12 percent of adults. Multiple retrospective studies have demonstrated a marked reduction in migraine symptoms following PFO closure. As such, the worldwide market potential for PFO closure to treat migraine patients has been estimated to be more than $15 billion per year.

About the Coherex FlatStent PFO Closure System

The Coherex FlatStent PFO Closure System is similar in use and function to self-expanding vascular stents which are widely used by Interventional Cardiologists. However, Coherex' patent-pending FlatStent Closure System incorporates a unique fusion of PFO closure mechanisms and accepted medical practices in a design expected to naturally seal a PFO tunnel.

About Coherex Medical

Formed in 2003 by Brian Whisenant, M.D., Coherex Medical is focused on addressing structural heart disease and conditions through medical devices. For more information, please visit www.coherex.com or call 801-433-9900.

Coherex and FlatStent are trademarks of Coherex Medical, Inc. All other trademarks are the properties of their respective owners.
COPYRIGHT 2007 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2007, Gale Group. All rights reserved.

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Date:Oct 21, 2007
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