Few infectious complications after BMT for breast cancer.Women who undergo autologous bone marrow transplantation autologous bone marrow transplantation Transplantation medicine The administration to an individual 'X' of his/her own BM, often to a leukemic Pt in relapse who, because a suitable HLA-matched donor is not available, would otherwise die of the disease. See Bone marrow. (BMT) or peripheral stem cell transplantation peripheral stem cell transplantation Peripheral stem cell support Oncology A method of replacing hematopoietic cells–HCs destroyed by chemotherapy; stem cells in circulating blood are removed before treatment, then readministered treatment to help BM recovery (PSCT) plus high-dose chemotherapy for breast cancer experience few infectious complications, according to researchers at the University of Pennsylvania Medical Center in Philadelphia. In their study of 127 women, the investigators found bacteremia, caused by a variety of gram-positive and gram-negative bacteria, was the most common infection immediately posttransplant, occurring in 13% of patients. Clostridium difficile colitis Clostridium difficile colitis Infectious disease Colonic infection by C difficile Clinical Some are asymptomic and become C difficile carriers; more commonly, diarrhea, abdominal pain, colitis, fever, vomiting dehydration; if severe, pseudomembranous and urinary tract infection urinary tract infection (UTI), n infection in one or more of the structures that make up the urinary system. Occurs more often in women and is most commonly caused by bacteria. were other causes of early infections following BMT or PSCT. Most infections during hospitalization (16%) were catheter-related, although 11% of patients developed mucocutaneous mucocutaneous /mu·co·cu·ta·ne·ous/ (-ku-ta´ne-us) pertaining to or affecting the mucous membrane and the skin. mu·co·cu·ta·ne·ous adj. Of or relating to the skin and a mucous membrane. candidiasis. Among the 32 patients who developed infections after hospital discharge, upper respiratory tract infections and dermatomal zoster dominated. Viral and fungal infections were uncommon after transplantation, and only 4 patients required hospitalization for infectious complications during the year of study follow-up. Clinical Infectious Disease 2001;32:391-395. |
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