Examine how to Meet the Highest Purity Standards in the Manufacture of Chiral Pharmaceuticals, Food Additives & Related Compounds.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c44918) has announced the addition of Chiral chi·ral  i·ty (k -r l Separation Techniques: A Practical Approach to their offering. Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide. The content scope of this new edition has significantly increased, due to the appearance of novel technologies in small- and large-scale separation of chiral products. Among the highlights are novel chapters on racemic separation by capillary 1. pertaining to or resembling a hair. 2. one of the minute vessels connecting the arterioles and venules, the walls of which act as a semipermeable membrane for interchange of various substances between the blood and tissue fluid. arterial capillary electrophoresis counter electrophoresis counterimmunoelectrophoresis. e·lec·tro·pho·re·sis (  -l k tr and on-line analysis of chiral compounds using mass spectrometry or biosensors. Existing chapters on chiral separations and analysis procedures have also been thoroughly updated and referenced to the most recent literature. From reviews of the first edition: Publication of this book is timely, and of immense value to the growth of this field Journal of Food Science A team of experts from academic and industrial laboratories throughout the world have compiled their findings and experience to make this book an exceptionally timely and unique contribution to the field European Journal of Drug Metabolism The dense mass of information contained in this book will make it a valuable resource ... Chemical Engineering Research This is a worthwhile addition to the expanding chiral literature and the book should be of value to those working in this field The Analyst This book is a valuable reference and should find a readership among scientists in the field of pharmaceutical sciences. Chirality This book can be recommended to analysts confronted with chiral separations. Journal of Chromatography A In conclusion this is a useful volume written on the whole by workers in the field and deserving a place in the bench of doing chiral separations. Human and Experimental Technology "Outstanding international contributors have agreed to share their knowledge and experience with the engaged readers and have compiled a valuable source in this special important scientific field. Each chapter of this book represents an overview of its chosen topic." - Advances in Food Sciences, 2001; Vol. 23; No. 1 Author information With over 30 years experience in both industry and academia, Ganapathy Subramanian is a biotechnology consultant working in the application and development of processing, purification methodologies and chromatographic systems for large-scale use in environmental science, food science, perfumery cosmetics and pharmaceuticals. He has also taught extensively in the area of food and medical technology. A chemistry graduate from Madras, India, he gained his doctorate from the University of Glasgow for work on natural products, and his main research interests lie in the utilization of natural material separation processes and bio-conversions. Dr. Subramanian has written and edited a number of books and articles in the field of biotechnology. For the last 10 years, he has been organizing conferences promoting the integration and knowledge exchange between academia and industry. Topics Covered 1 Enantiomeric separations using macrocyclic glycopeptide glycopeptide /gly·co·pep·tide/ (-pep´tid) any of a class of peptides that contain carbohydrates, including those that contain amino sugars. gly·co·pep·tide (gl stationary phases 2 The Role of Polysaccharides pol·y·sac·cha·rid (-r d) or pol·y·sac·cha·rose (-r s in Chiral Separations by Liquid Chromatography and Capillary Electrophoresis 3 Analytical and preparative potential of immobilized polysaccharide-derived chiral stationary phases 4 Chiral separations using supercritical fluid chromatography 5 Chiral ligand exchange in HPLC HPLC - High Performance Liquid Chromatography HPLC - High Pressure Liquid Chromatography HPLC - High Purity Liquid Chromatography and CE 6 Advances in Simulated Moving Bed Chromatographic separations 7 Less common applications of enantioselective HPLC using the SMB technology in the pharmaceutical industry 8 Enatiomer Separation by Chiral Crown Ether Stationary phases 9 Chiral Separation of amino acids and hydroxy acids in HPLC with copper(II) complexes added to the eluent 10 Chiral Capillary Electrophoresis 11 Techniques in preparative chiral separations 12 Separation of enantiomers using molecularly imprinted polymers 13 Enantioselective Biosensors 14 Chiral analysis using CEC-UV and CEC-MS 15 Chiral analysis using MEKC MEKC - Micellar Electrokinetic Chromatography-UV and MEKC-MS 16 Polarimeter polarimeter: see polarization of light. Chiral Detectors in Enantioseparations 17 Preparative Chiral Chromatography a powerful and efficient tool in drug discovery For more information visit http://www.researchandmarkets.com/reports/c44918 |
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