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Examine Detailed Profiles of Key Compounds in Development for Use in Bipolar Disorder, With Forecasts of Drug Revenues To 2015.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c42440) has announced the addition of the new report from Datamonitor "Pipeline Insight: Bipolar Disorder bipolar disorder, formerly manic-depressive disorder or manic-depression, severe mental disorder involving manic episodes that are usually accompanied by episodes of depression.  - New Treatments for Bipolar Depression Set to Drive Near-term Growth" to their offering.

Stimulated by sales of atypical antipsychotics for bipolar depression, and despite the launch of generic risperidone, the global bipolar disorder market will grow until 2011, when revenues will peak at $6.6 billion. The market will begin to decline thereafter owing to owing to
prep.
Because of; on account of: I couldn't attend, owing to illness.

owing to prepdebido a, por causa de 
 the launch of generic versions of the leading atypical antipsychotics, quetiapine, olanzapine, and ziprasidone from 2011 onwards.

Highlights of this title include:

AstraZeneca will be the first company to bring an atypical antipsychotic to the bipolar depression market as a monotherapy, following demonstration of efficacy with quetiapine. Pfizer will maintain a strong schizophrenia franchise by releasing asenapine to buffer the loss in revenue due to genericization of ziprasidone.

Solvay/Wyeth/Lundbecks bifeprunox will be the leading market entrant in terms of bipolar disorder specific sales revenue. These companies appear to be seeking initial license for bifeprunox in the bipolar depression indication, a tactic that will both increase the commercial viability of the drug and save time/money.

Despite the commercial success of Lamictal (lamotrigine) and Depakote (valproate valproate /val·pro·ate/ (val-pro´at) a salt of valproic acid; the sodium salt has the same uses as the acid.

val·pro·ate
n.
), the late-stage bipolar disorder pipeline only includes one anticonvulsant anticonvulsant /an·ti·con·vul·sant/ (-kon-vul´sant) inhibiting convulsions, or an agent that does this.

an·ti·con·vul·sant
n.
A drug that prevents or relieves convulsions.
 class molecule, Novartis licarbazepine.

Scope of this title:

This report provides an analysis of patient potential, unmet needs and clinical trial design in bipolar disorder. It also gives an overview of drugs in pre-registration, Phase III Noun 1. phase III - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA , II and I; with analysis of key companies involved in the market. The report gives detailed profiles of key compounds in development for use in bipolar disorder, with forecasts of drug revenues to 2015. It also discusses expansion strategies and insight from key industry opinion leaders.

Reasons to order your copy:

This report helps readers to understand unmet needs in the bipolar disorder market based on key opinion leader comments. It benchmarks key late-stage bipolar disorder compounds against current market leaders. It provides an assessment of the global (US, Japan, five major EU) sales forecasts of late-stage pipeline drugs; and examine their clinical and commercial potential.

Key Topics Covered Include:

--Patient potential

--Definition of bipolar disorder

--Characteristics of bipolar disorder phases

--Segmentation of bipolar disorder subtypes

--Bipolar I disorder

--Bipolar II disorder

--Bipolar III disorder (cyclothymia cyclothymia /cy·clo·thy·mia/ (si?klo-thi´me-ah) cyclothymic disorder.

cy·clo·thy·mi·a
n.
A mild mood disorder characterized by alternating periods of elation and depression.
)

--Current treatment paradigms for bipolar disorder

--Treatment of manic episodes associated with bipolar disorder

--Maintenance and prophylactic therapy

--Treatment of bipolar depression

--Off-label use of antidepressants Antidepressants
Medications prescribed to relieve major depression. Classes of antidepressants include selective serotonin reuptake inhibitors (fluoxetine/Prozac, sertraline/Zoloft), tricyclics (amitriptyline/ Elavil), MAOIs (phenelzine/Nardil), and heterocyclics
 for bipolar disorder treatment

--Classification of pipeline drugs seeking indication in bipolar disorder

--Positive and Negative Syndrome Scale

--Generic incursion in·cur·sion  
n.
1. An aggressive entrance into foreign territory; a raid or invasion.

2. The act of entering another's territory or domain.

3.
 expected when key CNS See Continuous net settlement.

CNS

See continuous net settlement (CNS).
 products come off-patent

--Follow-on antipsychotic antipsychotic /an·ti·psy·chot·ic/ (-si-kot´ik) effective in the treatment of psychotic disorders; also, an agent that so acts. Antipsychotics are a chemically diverse but pharmacologically similar class of drugs; besides psychotic  may not be sufficiently differentiated

--Drug overview: indication expansion into bipolar depression imminent

For more information visit http://www.researchandmarkets.com/reports/c42440

Source: Datamonitor
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Date:Sep 20, 2006
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