Ethical, Legal, and Social Implications of Human Genetics and Genomic Research.This program announcement replaces the regular research grant (R01) component of PA-96-042, "The Ethical, Legal, and Social Implications of Genetics Research." This program announcement is designed to solicit research projects that anticipate, analyze, and address the ethical, legal, and social implications of the discovery of new genetic technologies and the availability and use of genetic information resulting from human genetics Human genetics A discipline concerned with genetically determined resemblances and differences among human beings. Technological advances in the visualization of human chromosomes have shown that abnormalities of chromosome number or structure are surprisingly and genomic research. Of particular interest are studies that examine 1) the issues surrounding the completion of the human DNA sequence DNA sequence Genetics The precise order of bases–A,T,G,C–in a segment of DNA, gene, chromosome, or an entire genome. See Base pair, Base sequence analysis, Chromosome, Gene, Genome. and the study of human genetic variation; 2) the issues raised by the integration of genetic technologies and information into health care and public health activities; 3) the issues raised by the integration of knowledge about genomics and gene-environment interactions Gene-environment interaction is a term used to describe any phenotypic effects that are due to interactions between the environment and genes. Naive nature versus nurture debates assume that variation in a given trait is primarily due to either genes, or the individual's into nonclinical settings; 4) the ways in which new genetic knowledge may interact with a variety of philosophical, theological, and ethical perspectives; and 5) how socioeconomic so·ci·o·ec·o·nom·ic adj. Of or involving both social and economic factors. socioeconomic Adjective of or involving economic and social factors Adj. 1. factors, gender, and concepts of race, ethnicity, and culture influence the use and interpretation of genetic information, the utilization of genetic services, and the development of policy. This program announcement emphasizes the ongoing commitment of the National Institutes of Health to support research, and educational activities related to these and other ethical, legal, and social implications of human genetics and genomic research. The ultimate mission of the research program is to support research and education activities that 1)promote genetic privacy and fair use of genetic information, 2) encourage the responsible integration of new genetic information and technologies into clinical and nonclinical settings, 3) ensure that genetic research is conducted in an ethical manner, and 4) improve public and professional understanding about genetics, genome technology, and related ethical, legal, and social issues. Also of interest are studies that examine conceptual education or literacy issues such as what constitutes genetic literacy and how various audiences learn genetic information. Additional information is available on the Internet at http://grants.nih.gov/grants/guide/ pa- files/PA-00-133.html. Contact: The ELSI ELSI Ethical, Legal and Social Implications (of Human Genome Project) ELSI East London Somali Initiative (UK) Research Program, National Human Genome The human genome is the genome of Homo sapiens, which is composed of 24 distinct pairs of chromosomes (22 autosomal + X + Y) with a total of approximately 3 billion DNA base pairs containing an estimated 20,000–25,000 genes. Research Institute, Building 31, Room B2B (Business to Business) Refers to one business communicating with or selling to another. See B2B e-commerce, B2C and B2G. B2B - business to business 07, 31 Center Drive, MSC (1) (MSC.Software Corporation, Santa Ana, CA, www.mscsoftware.com) Founded in 1963 by Richard H. MacNeal and Robert G. Schwendler, MSC is the world's largest provider of mechanical computer aided engineering (MCAE) strategies, simulation software and services. 2033, Bethesda, MD 20892-2033 USA, 301-402-4997, fax: 301-402-1950, e-mail: elsi@nhgri.nih.gov. Reference: PA No. PA-00-133 |
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