Erratum.
Table 8. Development of definite/probable CBD and
sensitization by average cumulative, average mean,
and peak exposure ([+ or -] SE).
Disease No. of
outcome individuals
Definite/
Probable CBD 40
Sensitization 37
Normal 377
Mean
cumulative
exposure
([micro] Mean
Disease g-year/ exposure
outcome [m.sup.3]) (days)
Definite/
Probable CBD 181 [+ or -] 29 3483 [+ or -] 50
Sensitization 100 [+ or -] 23 (a) 1934 [+ or -] 5 (b)
Normal 209 [+ or -] 16 3359 [+ or -] 76
Mean Mean
average peak
exposure exposure
Disease (mg/ (mg/
outcome [m.sup.3]) [m.sup.3])
Definite/
Probable CBD 1.6 [+ or -] 0.21 3.1 [+ or -] 0.36
Sensitization 1.6 [+ or -] 0.16 2.9 [+ or -] 0.4
Normal 1.6 [+ or -] 0.06 3.3 [+ or -] 0.13
(a) p= 0.03 for sensitization vs. definite/probable and
p = 0.0003 for sensitization vs. normal.
(b) p = 0.047 for sensitization vs. definite/probable and
p = 0.02 for sensitization vs. normal.
Table 9. Development of definite/probable CBD and sensitization by
chemical form of beryllium, mixed, nonsoluble, and soluble: mean
cumulative, mean average, and mean peak exposure levels.
Mixed
Cumulative Mean Peak
([micro]g/ ([micro]g/ ([micro]g/
Disease outcome No. [m.sup.3]) [m.sup.3]) [m.sup.3])
Definite/
probable CBD 40 50 0.9 3.7
Sensitization 37 20 (b) 0.8 6.8
Normal 377 49 0.9 5.9
Nonsoluble
Cumulative Mean Peak
([micro]g/ ([micro]g/ ([micro]g/
Disease outcome [m.sup.3]) [m.sup.3]) [m.sup.3])
Definite/
probable CBD 126 1.7 5.1
Sensitization 61 (c) 1.6 5.1
Normal 128 1.6 6.1
Soluble
Cumulative Mean Peak
([micro]g/ ([micro]g/ ([micro]g/
Disease outcome [m.sup.3]) [m.sup.3]) [m.sup.3])
Definite/
probable CBD 5.8 (a) 0.9 1.1
Sensitization 19 0.8 3.3
Normal 26 0.9 2.7
(a) p < 0.0001 for definite/probable vs. normal.
(b) p= 0.0005 for sensitization vs. normal.
(c) p=0.04 for sensitization vs. definite/probable, and
p = 0.003 for sensitization vs. normal.
Table 10. Development of definite/probable CBD and sensitization by
physical form of beryllium, dust, fume, and mixed: mean
cumulative, mean average, and mean peak exposure levels.
Dust
Cumulative Mean Peak
([micro]g/ ([micro]g/ ([micro]g/
Disease outcome No. [m.sup.3]) [m.sup.3]) [m.sup.3])
Definite/
probable CBD 40 128 1.6 5.2
Sensitization 37 66 (c) 1.5 5.1
Normal 377 138 1.5 6.6
Fume
Cumulative Mean Peak
([micro]g/ ([micro]g/ ([micro]g/
Disease outcome [m.sup.3]) [m.sup.3]) [m.sup.3])
Definite/
probable CBD 4 (a) 0.5 0.8 (b)
Sensitization 17 0.9 3.3
Normal 20 0.6 1.9
Mixed
Cumulative Mean Peak
([micro]g/ ([micro]g/ ([micro]g/
Disease outcome [m.sup.3]) [m.sup.3]) [m.sup.3])
Definite/
probable CBD 49 0.9 3.7
Sensitization 17 (d) 0.8 6.8
Normal 46 0.9 5.9
(a) p < 0.0002 for definite/probable vs. normal.
(b) p = 0.04 for defintite/probable vs. normal.
(c) p = 0.0021 for sensitization vs. normal.
(d) p = 0.0004 for sensitization vs. normal.
Table 11. Development of definite/probable CBD and
sensitization by the American Conference of Governmental
and Industrial Hygienists notice of intended change,
current OSHA, and DOE DWA threshold levels.
Mean DWA exposure ([micro]g/
[m.sub.3]) [n (%)]
[greater
than
or
equal
0 to 0.02 to 0.2 to to]
Disease outcome < 0.02 < 0.2 < 2 2
Definite/probable CBD 0 (0) 0 (0) 33 (10) 7 (6)
Sensitization 0 (0) 0 (0) 24 (7) 13 (11)
Normal 0 (0) 3 (100) 279 (83) 95 (83)
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