Erratum.The abstract of the article beginning on page 93 of the January issue of Southern Medical Journal (Knox-Macaulay H, Ayyaril M, Nusrat N, Daar A. Colonic pseudo-obstruction in sickle cell disease sickle cell disease or sickle cell anemia, inherited disorder of the blood in which the oxygen-carrying hemoglobin pigment in erythrocytes (red blood cells) is abnormal. . South Med J 2003;96:93-95.) contained an important typographical error. The abstract is reprinted below with the correction incorporated: Abstract: A young Arab woman with sickle cell-[[beta].sub.0]-thalassemia disease developed acute colonic pseudo-obstruction that became chronic but showed some response to hydroxyurea hydroxyurea /hy·droxy·urea/ (-u-re´ah) an antineoplastic that inhibits a step in DNA synthesis, used in treatment of chronic granulocytic leukemia, some carcinomas, malignant melanoma, and polycythemia vera. . There was no evidence of microvascular or macrovascular occlusion. We also report the case of an Arab man with sickle cell anemia sickle cell anemia n. A chronic, usually fatal inherited form of anemia marked by crescent-shaped red blood cells, occurring almost exclusively in Blacks, and characterized by fever, leg ulcers, jaundice, and episodic pain in the joints. who presented with acute colonic pseudo-obstruction from which he recovered completely within a few days. Although the development of pseudo-obstruction in these two cases seems to have been a complication of sickle cell disease, its pathogenesis remains unclear. There are several reports of ischemic Ischemic An inadequate supply of blood to a part of the body, caused by partial or total blockage of an artery. Mentioned in: Antiangiogenic Therapy, Subarachnoid Hemorrhage, Ventricular Fibrillation ischemic and inflammatory disorders of the colon complicating sickle cell disease; however, these two cases represent the first descriptions of large-bowel pseudo-obstruction in this hemoglobinopathy hemoglobinopathy Any of a group of disorders caused by genetic abnormality of the hemoglobin molecule. The most prominent types are sickle-cell anemia and thalassemia, a set of disorders whose symptoms range from none to fatal anemia. . |
|
||||||||||||||

Printer friendly
Cite/link
Email
Feedback
Reader Opinion