Epilepsy find; In association with the NHS.
Studies in mice by American and Italian researchers linked seizures to brain changes that made immune cells stick inside its blood vessels.
This, in turn, the journal Nature Medicine reported, helped break down a vital filter which protects the brain from harmful chemicals.
Unsticking these cells helped prevent the development of epilepsy in mice.
The research may have found how an initial, non-epileptic, seizure could lead to a lifetime of epilepsy.
It looked at the behaviour of white blood cells whose job it is to defend the body from threats such as bacteria and viruses.
Scientists found that in mice the initial seizure caused the release of chemical in the blood vessels which increased the adhesion of leukocytes, keeping them in the vessels for longer.