Epidermal Growth Factor: Methods and Protocols.
Epidermal growth factor; methods and protocols.
Ed. by Tarun B. Patel and Paul J. Bertics.
Humana Press Inc.
Methods in molecular biology; 327
Epidermal growth factor (EGF) regulates a wide array of biological events, from normal development to pathological states including cancer and cardiovascular diseases. Patel (pharmacology and experimental therapeutics, Loyola U.-Chicago) and Bertics (biomolecular chemistry, U. of Wisconsin, Madison) introduce 14 chapters presenting a wide spectrum of reproducible protocols (in standard series' format) used to study this major therapeutic target. International researchers discuss approaches ranging from the study of the purified EGF receptor to complex signaling and processing networks in intact cells. With the EGF receptor system (mapped in a color diagram) now recognized for its role in many aggressive cancers, a chapter explores its pharmacological and clinical implications for cancer therapy.
([c]20062005 Book News, Inc., Portland, OR)