Eksigent Technologies Launches NanoLC-2D Proteomics System.
Business Editors/Health/Medical Writers
LIVERMORE, Calif.--(BUSINESS WIRE)--Jan. 22, 2004
Eksigent's Direct Pumping Nanoscale
HPLC HPLC high-performance liquid chromatography.
high performance liquid chromatography.
HPLC High-performance liquid chromatography Lab instrumentation A highly sensitive analytic method in which analytes are placed System is Now Available with the Added
Convenience of Automated 2-Dimensional Separations
Eksigent Technologies This article about a company does not make it clear whether the subject meets the Wikipedia criteria for . , a leader in the field of microfluidics, today announced the introduction of its NanoLC-2D Proteomics System. The NanoLC-2D System is the first HPLC (High Performance Liquid Chromatography High-performance liquid chromatography (HPLC) is a form of column chromatography used frequently in biochemistry and analytical chemistry. It is also sometimes referred to as high-pressure liquid chromatography. ) system to incorporate fully automated 2-dimensional HPLC separations with a direct pumping nanoscale HPLC system. The system provides significant enhancements in detection sensitivity and reproducibility for LC/MS LC/MS Liquid Chromatography/Mass Spectrometry proteomics studies, with the added convenience of automatically running 2-dimensional peptide separations, such as the frequently cited MudPIT method. The newly launched NanoLC-2D Proteomics system incorporates Eksigent's Microfluidic Flow Control (MFC (Microsoft Foundation Class) An application framework for writing Microsoft C/C++ and Visual C++ applications. See application framework.
MFC - Microsoft Foundation Class ) technology, which uses continuous feedback to an electronically controlled pressure source to maintain precise nanoscale flow rates without flow splitting. Instrument Business Outlook recently recognized the 1-dimensional version of the system, which was launched in 2003, as one of the leading systems for nanoscale chromatography.
The NanoLC-2D system will include a complete line of instruments and consumables. The system includes two binary gradient pump systems, autosampler, first and second dimension injection valves, control software, and separation columns. Dr. Karen Hahnenberger, NanoLC Product Manager, stated, "We are very excited to be launching the NanoLC-2D System. The system is extremely flexible; it can operate in automatic 2D mode, the first channel can be used for rapid sample loading, or both channels can run simultaneously as two completely independent binary gradient systems. In automatic 2D mode, the first dimension separation -- typically strong cation exchange cation exchange
A chemical process in which cations of like charge are exchanged equally between a solid, such as zeolite, and a solution, such as water. -- can be run as a step gradient or as a linear gradient. Furthermore, the NanoLC-2D system will include full integration with Thermo Electron's Xcalibur(R) mass spectrometer spectrometer
Device for detecting and analyzing wavelengths of electromagnetic radiation, commonly used for molecular spectroscopy; more broadly, any of various instruments in which an emission (as of electromagnetic radiation or particles) is spread out according to some software control."
According to according to
1. As stated or indicated by; on the authority of: according to historians.
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3. David Neyer, Ph.D., Technology Development Manager, "2-dimensional HPLC separations provide a significant increase in separation capacity versus 1-dimensional separations. The NanoLC-2D system combines automated 2-dimensional capability with the NanoLC system's precise nanoscale gradients, simple system operation, elimination of flow splitting, and automatic peak parking capability. This unique set of features makes the NanoLC-2D system ideally suited for multidimensional peptide analysis."
About Eksigent Technologies
Eksigent Technologies is pioneering microfluidic systems for use in proteomics, drug discovery, medical devices, and other life science applications. Eksigent's core microfluidic technologies include microscale pumping, micro-optics, and microfabrication. Products include the NanoLC system for highly sensitive Adj. 1. highly sensitive - readily affected by various agents; "a highly sensitive explosive is easily exploded by a shock"; "a sensitive colloid is readily coagulated" LC/MS, the Express system for high throughput analytical HPLC, and the EKPump for drug delivery. More information about the company is available at www.eksigent.com.